Diffusion Kurtosis Imaging to Assess Response to Treatment in Hypervascular Hepatocellular Carcinoma

Abstract

DKI can be a new option for the assessment of posttherapeutic response in HCC.

Diffusion kurtosis MRI versus conventional diffusion‐weighted imaging for evaluating inflammatory activity in Crohn's disease

“…The use of DKI to probe the non‐Gaussian behavior of water diffusion in solid organs has been reported in several studies . In the present study, D app and ADC values decreased, whereas K app increased with increasing activity of CD.…”

“…Although a maximum b‐value of 2000–2500 s/mm 2 was suggested in DKI of the brain, we set the highest b value at 2000 s/mm 2 because of lower signal‐to‐noise ratio (SNR) and faster signal decay of the transverse relaxation in the abdomen. Previous abdominal DKI studies have shown that the maximum b‐values of 800–2000 s/mm 2 were sufficient for estimating DKI parameter . Parallel imaging with short echo time of 80 msec was used in this study to improve the SNR.…”

Diffusion kurtosis imaging for differentiating borderline from malignant epithelial ovarian tumors: A correlation with Ki‐67 expression

“…The loose papillae, branching structure, and dense tiny cysts in BEOTs lead to a relatively easy diffusion of water molecules and therefore a higher ADC value . In addition, the studies showed that DKI was superior to standard DWI in assessment and early prediction of the response to treatment . Therefore, the DKI model may have potential advantages in the prediction or evaluation of the therapeutic effects of ovarian carcinomas.…”

“…The DKI model can better describe the complexity of the tissue microstructure. Recently, several studies have shown the advantage of DKI in tumor detection, grading, and response to treatment . However, the utility of ovarian DKI has not been reported.…”

Diffusion-weighted imaging of the liver: Current applications

“…Specifically, D* predicts lipiodol uptake[83]. DKI is reportedly a more reliable imaging biomarker than ADC[84]. …”