Diffusion and reaction controlled dissolution of oxygen microbubbles in blood

Fischer, Mathias; Zinovik, Igor; Poulikakos, Dimos

doi:10.1016/j.ijheatmasstransfer.2009.05.013

Cited by 9 publications

(13 citation statements)

References 36 publications

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“…Deep-sea sediments occupy the largest areal extent of the global ocean basins, yet they receive the lowest amounts of organic carbon [Dunne et al, 2007] and are thus characterized by deep oxygen penetration depths [Fischer et al, 2009;Røy et al, 2012]. Previous studies indicate that these areas may contain broad suboxic (absence of oxygen and sulfide) sedimentary zones (decimeter scale) [D'Hondt et al, 2009;Ziebis et al, 2012].…”

Section: Introductionmentioning

confidence: 99%

Quantifying manganese and nitrogen cycle coupling in manganese‐rich, organic carbon‐starved marine sediments: Examples from the Clarion‐Clipperton fracture zone

Mogollón

Mewes

Kasten

2016

Geophysical Research Letters

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Extensive deep‐sea sedimentary areas are characterized by low organic carbon contents and thus harbor suboxic sedimentary environments where secondary (autotrophic) redox cycling becomes important for microbial metabolic processes. Simulation results for three stations in the Eastern Equatorial Pacific with low organic carbon content (<0.5 dry wt %) and low sedimentation rates (10−1–100 mm ky−1) show that ammonium generated during organic matter degradation may act as a reducing agent for manganese oxides below the oxic zone. Likewise, at these sedimentary depths, dissolved reduced manganese may act as a reducing agent for oxidized nitrogen species. These manganese‐coupled transformations provide a suboxic conversion pathway of ammonium and nitrate to dinitrogen. These manganese‐nitrogen interactions further explain the presence and production of dissolved reduced manganese (up to tens of μM concentration) in sediments with high nitrate (>20 μM) concentrations.

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Section: Introductionmentioning

confidence: 99%

Quantifying manganese and nitrogen cycle coupling in manganese‐rich, organic carbon‐starved marine sediments: Examples from the Clarion‐Clipperton fracture zone

Mogollón

Mewes

Kasten

2016

Geophysical Research Letters

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“…Again, some of uses belong to the diffusion and/or reaction controlled transport phenomena -for example ref. [19] investigated transport and reaction-controlled dissolution of oxygen microbubbles in flowing blood. The most successful early application of microbubbles present in human body fluids was due to their ability to scatter and reflect ultrasound -enhancing substantially this diagnostic method [20].…”

Section: Biomedical Usesmentioning

confidence: 99%

What can be done with microbubbles generated by a fluidic oscillator? (survey)

Tesař

2017

EPJ Web Conf.

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Abstract.Recently discovered possibility of generating sub-millimetre bubbles by means of pulsating the inlet gas flow by a fluidic oscillator has opened a way to many interesting and advantageous engineering applications. Some of them have been known before, but were too inefficient and nearly forgotten. Now they deserve discussing in the new perspective. Other, applications, new ones, appear now in literature at a rapid pace. This paper, by providing a survey of already existing possibilities and advantages, aims at providing the readers an inspiration for their own developments.

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“…The dissolving process is determined by the Hill saturation curve, whereas the bonding process can be described as a chemical reaction with kinetic constants for the forward and reverse reactions [6]. The amount of oxygen bound to the haemoglobin is dependent on the P02 of the blood plasma surrounding the red blood cells, i. e. the oxygen needs to diffuse through the plasma to reach the red blood cells.…”

Section: Overview Of Bubble Dissolution Modellingmentioning

confidence: 99%

Development of an intravenous oxygenator using microbubbles

Elson

Scheffer

Dellimore

et al. 2014

2014 Cairo International Biomedical Engineering Conference (CIBEC)

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Patients in critical care with lung injuries require oxygenation, but current methods are not applicable for all situations. The most common method, Extracorporeal Membrane Oxygenation is an expensive procedure and requires highly trained staff. Respiratory Assist Catheters (RACs) could be used as an alternative because they do not place extra stress on the lungs, are easy to implement, cost effective and are available for immediate use in clinical settings or in first aid situations. This paper describes experiments and simulations to evaluate the feasibility of intravenously oxygenating the blood using microbubbles. The tests included in vivo and ex vivo tests using animal models to investigate both the dissolution times of the microbubbles as well as the physiological effects of an intravenously placed device. Numerical simulations based on the dissolution rate of oxygen in venous blood were also completed. The results indicate that the dissolution times for the micro bubbles are too slow for the device to be successful in clinical practice.

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Diffusion and reaction controlled dissolution of oxygen microbubbles in blood

Cited by 9 publications

References 36 publications

Quantifying manganese and nitrogen cycle coupling in manganese‐rich, organic carbon‐starved marine sediments: Examples from the Clarion‐Clipperton fracture zone

Quantifying manganese and nitrogen cycle coupling in manganese‐rich, organic carbon‐starved marine sediments: Examples from the Clarion‐Clipperton fracture zone

What can be done with microbubbles generated by a fluidic oscillator? (survey)

Development of an intravenous oxygenator using microbubbles

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