Diffuse Unilateral Subacute Neuroretinitis in South America

Souza, Eduardo Cunha de; Cunha, Sergio Lustosa da; Gass, J. Donald M.

doi:10.1001/archopht.1992.01080210079029

Cited by 38 publications

(34 citation statements)

References 9 publications

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“…Diffuse unilateral subacute neuroretinitis has been reported initially in America [7], and later in many other countries, including China [8], Brazil [6], and India [9]. This condition occurs more frequently in males than in females and most frequently in the second and third decade [6].…”

Section: Discussionmentioning

confidence: 99%

Intraocular nematode with diffuse unilateral subacute neuroretinitis: case report

et al. 2011

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BackgroundLive intraocular nematode is a rare occurrence. Nematode can migrate actively within the eye, creating visual symptoms and damaging ocular tissue.Case presentationA 26-year old man presented with painless reduced vision of the left eye for one week duration. It was associated with floaters. Visual acuity on the left eye was hand movement. Anterior segment examination was normal with normal intra-ocular pressure. Fundus examination showed a live nematode lying subretinally at the macular area with macular oedema and multifocal chorioretinal lesions at peripheral retina. There was no vitritis, vasculitis or any retinal hemorrhage. Systemic examination revealed normal findings and laboratory studies only showed leucocytosis with normal eosinophil count and negative serum toxocara antibody. The diagnosis of introcular nematode with diffuse unilateral subacute neuroretinitis was made. He was treated with oral anti-helminths and a course of oral steroid at a reducing dose. The nematode had died evidenced by its immobility during the treatment and finally disintegrated, leaving macular oedema with mottling appearance and mild hyperpigmentation. Multifocal chorioretinal lesions had also resolved. However despite treatment his visual acuity during follow-up had remained poor.ConclusionsCases of intraocular nematode, though not commonly encountered, continue to present the ophthalmologist with the problem of diagnosis and management and hence poorer prognosis to the patient.

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Section: Discussionmentioning

confidence: 99%

Intraocular nematode with diffuse unilateral subacute neuroretinitis: case report

et al. 2011

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“…This rare parasitic disease is relatively common in Brazil, preferentially affecting children and young adults 8. The differential diagnosis is hampered by the difficulty in finding the worm 9…”

Section: Discussionmentioning

confidence: 99%

Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging

Berbel¹,

Casella²,

Souza³

et al. 2014

OPTH

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BackgroundThe purpose of this study was to determine the value of spectral domain optical coherence tomography (SD-OCT) in assessing patients with diffuse unilateral subacute neuroretinitis (DUSN).MethodsThis was an observational case series with clinical imaging correlation performed at the Retina and Vitreous Institute of Londrina and State University of Londrina, Paraná, Brazil. The series comprised ten consecutive patients with a confirmed diagnosis of DUSN, ie, seven patients with late-stage disease and three with early-stage disease, who were assessed by SD-OCT for mean macular, retinal nerve fiber layer, and choroidal thickness using enhanced depth imaging software.ResultsComparing the affected eye with the healthy fellow eye, significant diffuse atrophy of the retinal layers with a decrease in mean macular (P=0.004) and retinal nerve fiber layer (P=0.002) thickness was found in all cases. There was no difference in choroidal thickness (P=0.262).ConclusionThe correlation of SD-OCT results with central vision and funduscopic findings may explain the profound loss of visual function in patients with DUSN.

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“…The small nematode variant of DUSN may be caused by Toxocara spp. (400 μ m) or hookworm larvae ( Ancylostoma caninum or others; 500–700 μ m), both parasites implicated in DUSN cases in the southeastern United States, Caribbean, and South America [4,6,7,10]. At least two cases of DUSN have also been caused by trematode larvae ( Alaria spp.)…”

Section: Discussionmentioning

confidence: 99%

“…Care has to be taken not to lose sight of the worm, since it may disappear from view or escape into the vitreous, necessitating surgical removal [3, 7,18]. Systemic anthelmintic therapy does not appear to be universally effective, but may be considered if no worm can be found, or if there is suspicion of bilateral involvement or presence of another worm, and obviously in the case of concomitant systemic involvement [4,6]. …”

Section: Discussionmentioning

confidence: 99%

Baylisascaris Procyonis Induced Diffuse Unilateral Subacute Neuroretinitis in New York City

Saffra¹,

Perlman²,

Desai³

et al. 2010

J. Neuroparasitolog.

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Diffuse unilateral subacute neuroretinitis (DUSN) secondary to raccoon roundworm (Baylisascaris procyonis) infection has been reported in rural and suburban areas of North America and Europe with extant raccoon populations. Here, we present a case of Baylisascaris-induced DUSN from the densely populated borough of Brooklyn in New York City and alert urban ophthalmologists to consider this etiology even in areas not typically thought to be associated with endemic risk factors. Infected raccoons also occur in urban settings, and urban patients may be exposed in surrounding areas. Most patients with Baylisascaris ocular larva migrans-DUSN will not have concomitant neurologic disease; this fact and larval neurotropism are both misconceptions regarding this infection.

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Diffuse Unilateral Subacute Neuroretinitis in South America

Cited by 38 publications

References 9 publications

Intraocular nematode with diffuse unilateral subacute neuroretinitis: case report

Intraocular nematode with diffuse unilateral subacute neuroretinitis: case report

Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging

Baylisascaris Procyonis Induced Diffuse Unilateral Subacute Neuroretinitis in New York City

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