Diffuse unilateral subacute neuroretinitis

Anshu, Arundhati; Chee, Soon Phaik

doi:10.1007/s10792-007-9117-y

Cited by 8 publications

(2 citation statements)

References 4 publications

(2 reference statements)

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“…ERG can be used to assess the functional status of the retina. Studies have shown that a- and b-wave amplitude was reduced in the affected eye in all stages of the disease4,10–12 and that b-wave is normally affected more than a-wave (Table 1). The unaffected eye has normal ERG findings.…”

Section: Discussionmentioning

confidence: 99%

Diffuse unilateral subacute neuroretinitis in a young boy: a case report

Guan-Fook¹,

Hayati²,

Raja-Azmi³

et al. 2012

OPTH

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We report a case of diffuse unilateral subacute neuroretinitis in a young boy with no clinical visualization of nematode. The diagnosis was made based on clinical findings and detection of Toxocara immunoglobulin G by Western blot test. An 11-year-old Malay boy presented with progressive blurring of vision in the left eye for a duration of 1 year. It was associated with intermittent floaters. Visual acuity in the left eye was 6/45 and improved to 6/24 with pinhole. There was positive relative afferent pupillary defect, impaired color vision, and presence of red desaturation in the left eye. There were occasional cells in the anterior chamber with no conjunctiva injection. Posterior segment examination revealed mild-to-moderate vitritis and generalized pigmentary changes of the retina with attenuated vessels. The optic disk was slightly hyperemic with mild edema. There was presence of multiple, focal, gray-white subretinal lesions at the inferior part of the retina. Full blood picture results showed eosinophilia with detection of Toxocara immunoglobulin G by Western blot test. Investigations for other infective causes and connective tissue diseases were negative. The diagnosis of diffuse unilateral subacute neuroretinitis secondary to Toxocara was made based on clinical findings and laboratory results. He was treated with oral albendazole 400 mg daily for 5 days and oral prednisolone 1 mg/kg with tapering doses over 6 weeks. At 1 month follow-up, the inflammation had reduced, and multiple, focal, gray-white subretinal lesions were resolved; however there was no improvement of vision.

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Section: Discussionmentioning

confidence: 99%

Diffuse unilateral subacute neuroretinitis in a young boy: a case report

Guan-Fook¹,

Hayati²,

Raja-Azmi³

et al. 2012

OPTH

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“…If a worm is not found clinically, appearance of sub-RPE serpiginous tract in the inferotemporal retina, peripheral RPE hypopigmentation, good clinical response to anti-helminthics, and abnormal ERG supports the diagnosis. [49] Treatment with albendazole is beneficial.…”

Section: Infective Posterior Uveitismentioning

confidence: 99%

Current approach in the diagnosis and management of posterior uveitis

Sridharan

Ganesh

Biswas

2010

Indian J Ophthalmol

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Posterior uveitic entities are varied entities that are infective or non-infective in etiology. They can affect the adjacent structures such as the retina, vitreous, optic nerve head and retinal blood vessels. Thorough clinical evaluation gives a clue to the diagnosis while ancillary investigations and laboratory tests assist in confirming the diagnosis. Newer evolving techniques in the investigations and management have increased the diagnostic yield. In case of diagnostic dilemma, intraocular fluid evaluation for polymerase chain testing for the genome and antibody testing against the causative agent provide greater diagnostic ability.

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