Diffuse-Type Tenosynovial Giant Cell Tumor of the Thoracic Spine

Shen, Guohua; Ma, Huan; Pan, Lili; Su, Minggang; Kuang, Anren

doi:10.1097/rlu.0000000000002541

Cited by 7 publications

(9 citation statements)

References 11 publications

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“…In the present study, GCTTSs showed moderate to marked enhancement, probably due to the proliferative capillaries within the collagenous stroma within the lesion [10]. 18 F-FDG PET/CT imaging of spinal GCTTS has been infrequently reported [11][12][13][14]. In previous studies, GCTTS showed a high 18 F-FDG uptake [11][12][13][14].…”

Section: Discussionsupporting

confidence: 57%

“…18 F-FDG PET/CT imaging of spinal GCTTS has been infrequently reported [ 11 – 14 ]. In previous studies, GCTTS showed a high 18 F-FDG uptake [ 11 – 14 ].…”

Section: Discussionmentioning

confidence: 99%

“…18 F-FDG PET/CT imaging of spinal GCTTS has been infrequently reported [ 11 – 14 ]. In previous studies, GCTTS showed a high 18 F-FDG uptake [ 11 – 14 ]. All the lesions in our study showed high 18 F-FDG uptake, consistent with previous report findings.…”

Section: Discussionmentioning

confidence: 99%

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Giant cell tumour of the tendon sheath of the spine: clinical features and imaging findings

et al. 2021

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Objectives To review the clinical and imaging data of spinal giant cell tumour of the tendon sheath (GCTTS) to improve our understanding of the disease. Methods The imaging findings, clinicopathological features and clinical outcomes of 14 patients with pathologically confirmed spinal GCTTS were analysed retrospectively. Results All 14 patients had a single spinal lesion, including ten cervical vertebra lesions and four thoracic vertebra lesions. CT scan findings: The lesions showed osteolytic bone destruction and were centred on the facet joint, eroding the surrounding bone with a paravertebral soft tissue mass. MRI scan findings: all the lesions manifested predominantly as isointense or hypointense on T1-weighted imaging (T1WI). On T2-weighted imaging (T2WI), eight lesions were hypointense, and four were isointense. The remaining two lesions showed slight hyperintensity. The enhanced scans of eight lesions showed moderate to marked homogeneous or heterogeneous enhancement. PET/CT findings: Among the five patients who underwent PET/CT, three presented lesions with well-defined, sclerotic borders, and the uptake of 18F-FDG was markedly increased. One lesion showed an ill-defined border and an uneven increase in 18F-FDG uptake with an SUVmax value of 8.9. A recurrent lesion was only found on PET/CT 45 months after surgery and the SUVmax was 5.1. Conclusions Spinal GCTTS is extremely rare. Osteolytic bone destruction in the area of the facet joint with a soft tissue mass and hypointensity on T2WI images are indicative of the spinal GCTTS. GCTTS shows high uptake of 18F-FDG, and PET/CT is helpful in detecting recurrent lesions.

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Section: Discussionsupporting

confidence: 57%

“…18 F-FDG PET/CT imaging of spinal GCTTS has been infrequently reported [ 11 – 14 ]. In previous studies, GCTTS showed a high 18 F-FDG uptake [ 11 – 14 ].…”

Section: Discussionmentioning

confidence: 99%

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Giant cell tumour of the tendon sheath of the spine: clinical features and imaging findings

et al. 2021

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“…G iant cell tumor of the tendon sheath (GCTTS) is a slowly progressive neoplasm originating from the synovial cells in the bursa, tendon sheath, and joints, which highly impacts the quality of life. [1][2][3][4] This neoplasm rarely occurs in the spine, and only about 85 spinal cases have been reported in the past few decades. 4,5 Surgical management has been adopted as a conventional method for treating spinal GCTTS.…”

mentioning

confidence: 99%

3D-printed Titanium Prosthetic Reconstruction of Unilateral Bone Deficiency After Surgical Resection of Tumor Lesions in the Upper Cervical Spine

Shen

Yang²,

Zhong³

et al. 2023

Clinical Spine Surgery: A Spine Publication

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Main points: Operational excision of tumor lesions in the upper cervical spine remains a tremendous challenge to surgeons due to the local complex anatomic relationships. Meanwhile, no commercially available device has been specially designed to address bone deficiency after surgical resection. Here, we described the reconstruction of unilateral bone deficiency after surgical resection of a giant cell tumor of the tendon sheath originating from the lateral atlantoaxial joint with the employment of a 3D printing technique and reviewed the relevant literature. In our study, 3 patients with giant cell tumor of the tendon sheath in the upper cervical spine achieved complete tumor removal, and received unilateral bone reconstruction with one-armed 3D-printed titanium prosthesis. During the follow-up, these patients remained neurologically intact and got back to a normal life without wearing the braces. Images demonstrated the satisfactory placement of 3D-printed prosthesis with no failure of fixation and no subsidence. In addition, 6 articles describing the employment of 3D-printed prostheses or models for tumor surgery in the upper cervical spine were reviewed, and satisfactory clinical outcomes were reported in these studies. Hence, 3D-printed titanium prosthetic reconstruction of bone deficiency in the upper cervical spine was a safe and effective technique. Level of Evidence: Level IV.

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“…2 Several case reports and small series have shown that tenosynovial giant cell tumor can show increased FDG uptake and may cause false-positive result on FDG PET/CT. [6][7][8][9][10] FDG PET/CT findings of facet joints have been rarely reported before. This case indicates tenosynovial giant cell tumor, although rare, should be included in the differential diagnosis of abnormal facet joint FDG accumulation.…”

mentioning

confidence: 99%

FDG PET/CT in Tenosynovial Giant Cell Tumor of the Lumbar Facet Joint

Zhang

Zhu

et al. 2021

Clin Nucl Med

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Tenosynovial giant cell tumor rarely affects the facet joints of the spine. We describe FDG PET/CT findings in a case of tenosynovial giant cell tumor arising from the left L2 to L3 facet joint. The tumor caused osteolytic bone destruction of the facet joint and showed intense FDG uptake with SUV max of 10.4. This case indicates tenosynovial giant cell tumor should be included in the differential diagnosis of abnormal facet joint FDG accumulation.

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Diffuse-Type Tenosynovial Giant Cell Tumor of the Thoracic Spine

Cited by 7 publications

References 11 publications

Giant cell tumour of the tendon sheath of the spine: clinical features and imaging findings

Giant cell tumour of the tendon sheath of the spine: clinical features and imaging findings

3D-printed Titanium Prosthetic Reconstruction of Unilateral Bone Deficiency After Surgical Resection of Tumor Lesions in the Upper Cervical Spine

FDG PET/CT in Tenosynovial Giant Cell Tumor of the Lumbar Facet Joint

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