Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma

Jung, Hyun Hwan; Hong, Soon Won; Kim, Min Jung; Yoon, Jung Hyun; Kwak, Jin Young

doi:10.7863/jum.2013.32.2.347

Cited by 13 publications

(10 citation statements)

References 15 publications

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“…Incalculable nodule-independent microcalcifications A large number of incalculable nodule-independent microcalcifications that are typically snowstorm-like are diffusely scattered in the whole or large area of unilateral or bilateral thyroid gland, which is always seen in the diffuse sclerosing variant of PTC [142,143]. If typical cervical metastatic lymph nodes of thyroid cancer are observed, these findings are assessed to belong to C-TIRADS category 5 (Fig.…”

Section: Classification Of Special Casesmentioning

confidence: 99%

2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS

et al. 2020

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Thyroid nodules are very common all over the world, and China is no exception. Ultrasound plays an important role in determining the risk stratification of thyroid nodules, which is critical for clinical management of thyroid nodules. For the past few years, many versions of TIRADS (Thyroid Imaging Reporting and Data System) have been put forward by several institutions with the aim to identify whether nodules require fine-needle biopsy or ultrasound follow-up. However, no version of TIRADS has been widely adopted worldwide till date. In China, as many as ten versions of TIRADS have been used in different hospitals nationwide, causing a lot of confusion. With the support of the Superficial Organ and Vascular Ultrasound Group of the Society of Ultrasound in Medicine of the Chinese Medical Association, the Chinese-TIRADS that is in line with China's national conditions and medical status was established based on literature review, expert consensus, and multicenter data provided by the Chinese Artificial Intelligence Alliance for Thyroid and Breast Ultrasound.

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Section: Classification Of Special Casesmentioning

confidence: 99%

2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS

et al. 2020

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“…Solid and predominantly solid nodules are also more likely to be malignant compared to cystic nodules [32]. It is worth noting that the diffuse sclerosing variant of PTC may present as diffusely infiltrating disease resulting not in a single nodule but in diffuse enlargement of a lobe or the entire gland [33,34]. Diffuse thyroid enlargement, especially if accompanied by cervical lymphadenopathy, must therefore prompt imaging for the microcalcifications that are invariably associated with this subtype [33,35].…”

Section: Clinical Presentationmentioning

confidence: 99%

Thyroid Cancer in the Pediatric Population

Paulson

Rudzinski

Hawkins

2019

Genes

175

172

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Thyroid cancer is rare in the pediatric population, but thyroid carcinomas occurring in children carry a unique set of clinical, pathologic, and molecular characteristics. In comparison to adults, children more often present with aggressive, advanced stage disease. This is at least in part due to the underlying biologic and molecular differences between pediatric and adult thyroid cancer. Specifically, papillary thyroid carcinoma (which accounts for approximately 90% of pediatric thyroid cancer) has a high rate of gene fusions which influence the histologic subtypes encountered in pediatric thyroid tumors, are associated with more extensive extrathyroidal disease, and offer unique options for targeted medical therapies. Differences are also seen in pediatric follicular thyroid cancer, although there are few studies of non-papillary pediatric thyroid tumors published in the literature due to their rarity, and in medullary carcinoma, which is most frequently diagnosed in the pediatric population in the setting of prophylactic thyroidectomies for known multiple endocrine neoplasia syndromes. The overall shift in the spectrum of histotypes and underlying molecular alterations common in pediatric thyroid cancer is important to recognize as it may directly influence diagnostic test selection and therapeutic recommendations.

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“…If dots are present in both, they are probably not PEF for the purpose of ACR TI-RADS classification. The only exception is the diffuse sclerosing variant of papillary carcinoma, which should not present a problem in diagnosis (13).…”

Section: Reporting Considerationsmentioning

confidence: 99%

Thyroid Imaging Reporting and Data System (TI-RADS): A User’s Guide

2018

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In 2017, the Thyroid Imaging Reporting and Data System (TI-RADS) Committee of the American College of Radiology (ACR) published a white paper that presented a new risk-stratification system for classifying thyroid nodules on the basis of their appearance at ultrasonography (US). In ACR TI-RADS, points in five feature categories are summed to determine a risk level from TR1 to TR5. Recommendations for biopsy or US follow-up are based on the nodule's ACR TI-RADS level and its maximum diameter. The purpose of this article is to offer practical guidance on how to implement and apply ACR TI-RADS based on the authors' experience with the system. RSNA, 2018.

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Diffuse Sclerosing Variant of Papillary Thyroid Carcinoma

Cited by 13 publications

References 15 publications

2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS

2020 Chinese guidelines for ultrasound malignancy risk stratification of thyroid nodules: the C-TIRADS

Thyroid Cancer in the Pediatric Population

Thyroid Imaging Reporting and Data System (TI-RADS): A User’s Guide

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