Diffuse-reflectance spectroscopy from 500 to 1060 nm by correction for inhomogeneously distributed absorbers

Veen, R.L.P. van; Verkruysse, Wim; Sterenborg, Henricus J. C. M.

doi:10.1364/ol.27.000246

Cited by 118 publications

(123 citation statements)

References 13 publications

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“…18 Light from a 100᎑W halogen light source is coupled into the sample by means of an optical fiber. Diffuse remitted light from the sample is collected at nine different sourcedetection fiber distances and is coupled into a spectrograph and projected onto a cooled ͑Ϫ35 ºC͒ CCD camera.…”

Section: Systems Enrolled In the Studymentioning

confidence: 99%

Performance assessment of photon migration instruments: the MEDPHOT protocol

et al. 2005

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We propose a comprehensive protocol for the performance assessment of photon migration instruments. The protocol has been developed within the European Thematic Network MEDPHOT (optical methods for medical diagnosis and monitoring of diseases) and is based on five criteria: accuracy, linearity, noise, stability, and reproducibility. This protocol was applied to a total of 8 instruments with a set of 32 phantoms, covering a wide range of optical properties.

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Section: Systems Enrolled In the Studymentioning

confidence: 99%

Performance assessment of photon migration instruments: the MEDPHOT protocol

et al. 2005

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“…Due to the fact that the diffusion approximation is not applicable, Monte Carlo has been the method of choice. The evaluation of the impact of tissue structure on optical diagnostic methods [16,17] and treatments [18] shows that non-homogeneity has often a non-negligible impact on average transport properties and radiation effects. The effect of macroscopic heterogeneity has also been investigated by means of Monte Carlo methods.…”

Section: Introductionmentioning

confidence: 99%

Shape based Monte Carlo code for light transport in complex heterogeneous Tissues

Margallo-Balbás

French

2007

Opt. Express

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A Monte Carlo code for the calculation of light transport in heterogeneous scattering media is presented together with its validation. Triangle meshes are used to define the interfaces between different materials, in contrast with techniques based on individual volume elements. This approach allows to address realistic problems in a flexible way. A hierarchical spatial organisation enables a fast photon-surface intersection test. The application of the new environment to evaluate the impact of the trabecular structure of bone on its optical properties is demonstrated. A model of the trabecular micro structure recovered from microCT data was used to compute light distribution within tissue. Time-resolved curves across a spherical bone volume were computed. The work presented enables simulation of radiative transport in complex reality-based models of tissue and serves as a powerful, generic tool to study the effect of heterogeneity in the field of biomedical optics. 547-560 (1998 193-206 (1998). 24. A. Pifferi, A. Torricelli, P. Taroni, A. Bassi, E. Chikoidze, E. Giambattistelli, and R. Cubeddu, "Optical biopsy of bone tissue: a step toward the diagnosis of bone pathologies," J. Biomed. Opt. 9(3), 474-479 (2004).

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“…Both the transmitted light (transmission or transillumination spectroscopy) and the diffusely reflected radiation (reflectance or backscattering spectroscopy) are detected. [179,199,200,203,204,211] techniques. The near IR spectroscopy makes use of the same principles and the same methods of data recording, as the modern optical imaging methods, based on the detection of diffusely scattered light, and in this sense is their direct predecessor.…”

Section: Methods Based On the Detection Of Diffusely Scattered Lightmentioning

confidence: 99%

Diffuse optical mammotomography: state-of-the-art and prospects

Konovalov

Genina

Bashkatov

2016

JBPE

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Abstract:The principles of diffuse optical tomography (DOT) of tissues are presented. The DOT capabilities as a method of breast cancer diagnostics are analysed. The state-ofthe-art of the DOT instrumentation and methodological base in application to solving the mammography problems are described. The significant contribution of Russian scientists to the development of the DOT methodology is emphasised. Basing on the results of the analysis, the authors expect the possibility of soonest entry of diffuse optical mammotomographs to the market of medical imaging instrumentation, and the capability of Russian researchers to take part in the competition for this market. © 2016 Journal of Biomedical Photonics & Engineering.Key words: diffuse optical tomography, breast, optical and functional parameters, methods of determining optical parameters, methods of image reconstruction, perturbation model of reconstruction, temporal point spread function, spatial resolution, reconstruction time. University Press, Cambridge (2016). 7. S. R. Arridge, and M. Schweiger, "Inverse methods for optical tomography," in Information Processing in Medical Imaging, H.H. Barrett (ed.), Springer-Verlag, Flagstaff, 259-277 (1993). 8. J. C. Hebden, S. R. Arridge, and D. T. Delpy, "Optical imaging in medicine: I. Experimental techniques,"Phys. Med. Biol. 42, 825-840 (1997). 9. S. R. Arridge, and J. C. Hebden, "Optical imaging in medicine: II. Modelling and reconstruction," Phys. Med. Biol. 42, 841-853 (1997). 10. B. B. Das, F. Liu, and R. R. Alfano, "Time-resolved fluorescence and photon migration studies in biomedical and random media," Rep. Prog. Phys. 60, 227-292 (1997). 11. K. Michielsen, H. De'Raedt, J. Przeslawski, and N. Garcia, "Computer simulation of time-resolved optical imaging of objects hidden in turbid media," Phys. Rep. 304, 89-144 (1998). 12. S. R. Arridge, "Optical tomography in medical imaging," Inverse Problems 15, R41-R93 (1999). Darzi, "Diffuse optical imaging of the healthy and diseased breast: a systematic review," Breast Cancer Research and Treatment 108, 9-22 (2008). 19. S. L. Jacques, and B. W. Pogue, "Tutorial on diffuse light transport," J. Biomed. Opt. 13, 041302 (2008 Biol. 361, 171-179 (1994). 31. A. Yodh, and B. Chance, "Spectroscopy and imaging with diffusing light," Phys. Today 48, 34-40 (1995). 32. J. C. Hebden, S. R. Arridge, "Imaging through scattering media by the use of an analytical model of perturbation amplitudes in the time domain," Appl. Opt. 35, 6788-6796 (1996). 33. K. D. Paulsen, and H. Jiang, "Enhanced frequency-domain optical image reconstruction in tissues through total-variation minimization," Appl. Opt. 35, 3447-3458 (1996). 34. R. J. Grable, "Optical tomography improves mammography," Laser Focus World 32, 113-118 (1996). 35. V. V. Lyubimov, "The physical foundation of the strongly scattering media laser tomography," Proc. SPIE 2769SPIE , 107-110 (1996. 36. V. V. Lyubimov, "Optical tomography of highly scattering media by using the first transmitted photons of ultrashort pulses," Optics a...

show abstract

Diffuse-reflectance spectroscopy from 500 to 1060 nm by correction for inhomogeneously distributed absorbers

Cited by 118 publications

References 13 publications

Performance assessment of photon migration instruments: the MEDPHOT protocol

Performance assessment of photon migration instruments: the MEDPHOT protocol

Shape based Monte Carlo code for light transport in complex heterogeneous Tissues

Diffuse optical mammotomography: state-of-the-art and prospects

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