Diffuse pneumatosis intestinalis and pneumoperitoneum

Mora-Guzmán, Ismael; Nova, José Luis Muñoz de; Val, Lourdes del Campo; Martín-Pérez, Elena

doi:10.1016/j.dld.2017.03.016

Cited by 4 publications

(4 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Laparoscopy should be considered in patients with PCI and pneumoperitoneum if leukocytosis and metabolic acidosis are present or if there is clinical worsening. Ischemia and hollow visceral perforation should be excluded 6,7,11,16,20,24,26,42,44,45 . Long-term outcomes are still not well known, with reports of complications that may or may not be associated with PCI, such as intestinal ischemia secondary to volvulus 24,47 .…”

Section: Discussionmentioning

confidence: 99%

“…Pneumatosis cystoides intestinalis (PCI) is a rare benign condition characterized by the presence of gas-filled cysts in the intestinal wall in the absence of intestinal infarction [1][2][3][4][5][6] . It has a worldwide incidence of 0.03% and is more common in men, with a 3:1 male-to-female ratio [1][2][3][4][5][6][7][8][9][10] . It was first described by DuVernoi et al in 1783, and its etiology and pathogenesis still remain unclear 2,7,8,[11][12][13][14][15][16] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Management of pneumatosis cystoides intestinalis with pneumoperitoneum: 5-years systematic review

Piltcher-da-Silva¹,

Sasaki²,

Gallotti³

et al. 2022

CBR

View full text Add to dashboard Cite

Introduction: Pneumatosis cystoides intestinalis (PCI) is a rare condition characterized by gas-filled cysts in the intestinal wall. Although rare, it may also involve other regions, such as the mesentery. PCI is classified as primary or secondary and is associated with multiple predisposing factors. It may be associated with either a benign condition or a potentially fatal condition, such as mesenteric ischemia. The objective of this study was to review the medical literature on the rare benign presentations of PCI, excluding cases associated with intestinal ischemia. Methods:We conducted a systematic literature review according to the PRISMA statement. We searched PubMed and LILACS databases for articles published between January 2015 and December 2020 using the following Medical Subject Headings: "pneumatosis cystoides intestinalis" and "pneumoperitoneum," "pneumatosis intestinalis," and "pneumoperitoneum" or "mesenteric pneumatosis." Results:We included 51 articles comprising 58 patients with PCI and pneumoperitoneum. Most patients were men, and mean patient age was 64.9 years. We identified an idiopathic etiology in 29.31% of cases, and the most common predisposing factor was immune dysfunction (29.31%). A total of 24.13% of patients were asymptomatic. The most commons symptoms were abdominal pain (43.10%), nausea and vomiting (41.37%), and abdominal distention (37.93%). Diagnostic surgery was conducted in 26 patients (44.82%). Only 1 patient underwent surgical treatment.Conclusions: PCI is a clinical condition that may have a benign etiology and not require surgery. Treatment of the benign etiology is conservative. Thus, life-threatening conditions should be excluded in all cases.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Management of pneumatosis cystoides intestinalis with pneumoperitoneum: 5-years systematic review

Piltcher-da-Silva¹,

Sasaki²,

Gallotti³

et al. 2022

CBR

View full text Add to dashboard Cite

show abstract

“…In the remaining 7 cases, the laparotomy yielded no benefit. Despite the fact that conservative management for ISP has been suggested for decades (3), the surgical community continues to offer ISP patients surgical intervention that might be unnecessary (5,6,7). If the patient did not exhibit signs of peritonitis, our review suggests there is no benefit to surgery.…”

Section: Case #2mentioning

confidence: 97%

Idiopathic Spontaneous Pneumoperitoneum: When Not to Operate

D.O.1¹,

Gogineni²,

3³

et al. 2019

IJCR

View full text Add to dashboard Cite

Pneumoperitoneum is often a surgical emergency related to gastrointestinal tract perforation. On rare occasions, free intraperitoneal air can be present without any discernible cause and is considered Idiopathic Spontaneous Pneumoperitoneum (ISP). Deciding which patients with ISP can be managed conservatively would help prevent some patients from undergoing unnecessary surgery. We describe here two cases of successful management of ISP and the review of literature of ISP management for the past 29 years. In the first case, a patient with ISP with no significant abdominal symptoms was successfully managed non-operatively. In the second case, a patient with ISP and symptoms of small bowel obstruction was successfully treated surgically with exploratory laparotomy and small bowel resection. We recommend conservative management for the subset of ISP patients with no sign of peritonitis or sepsis.

show abstract

“…This sensitivity in turn enables ion injection times of 3 ms, driving compatibility with novel methodologies such as narrow-bin DIA and rapid LC-MS/MS experiments, discussed in more depth below. [326][327][328][329] Beyond Q-Orbitraps and Q-TOFs, the versatility, sensitivity, speed, and stand-alone capabilities of ion traps drove their adoption into diverse instrument architectures, most notably in combination with high-resolution Orbitrap and FTICR mass analyzers. In the first generation Orbitrap systems, like the LTQ Orbitrap XL, 330 LTQ Orbitrap Velos, 331 and Orbitrap Elite 332 hybrid systems, the LIT functions as both the m/z isolation device and the reaction cell for ion activation, although a dedicated collision cell was introduced behind the C-trap in later models 333,334 and multipurpose dissociation cell options were explored.…”

Section: Common Hybrid Ms Architecturesmentioning

confidence: 99%

Instrumentation at the leading edge of proteomics

Peters-Clarke,

Coon,

Riley

2023

Preprint

View full text Add to dashboard Cite

The proteome, or collection of proteoforms expressed in a biological system, is dynamic and heterogeneous. As our appreciation for the complexity of the proteome has evolved, so have the technologies we use to interrogate its composition. More than three decades ago, a rapid expansion in the field of proteomics was driven by the advent of soft ionization techniques focusing on capturing protein sequence information using mass spectrometry (MS). As tools to automate peptide and protein sequencing with tandem MS (MS/MS) matured, our field recognized the limits of qualitatively cataloguing gene products.1,2 This realization drove a multi-pronged expansion of MS-centric technologies that seek to capture various aspects of proteins, including their abundance, modification states, conformation and structure, and spatiotemporal relationships.3–7 Here we review innovations in MS-based instrumentation that continue to expand our ability to survey the proteome with ever increasing sensitivity, speed, and flexibility. The march of progress in MS instrumentation has been steady over the better half of the past century, but our discussion here focuses on developments within the past five years that have ushered in an exciting era in proteomics, where MS is poised to be the dominant platform for exploring biological phenotypes in basic and translational sciences for the foreseeable future.

show abstract

Diffuse pneumatosis intestinalis and pneumoperitoneum

Cited by 4 publications

References 2 publications

Management of pneumatosis cystoides intestinalis with pneumoperitoneum: 5-years systematic review

Management of pneumatosis cystoides intestinalis with pneumoperitoneum: 5-years systematic review

Idiopathic Spontaneous Pneumoperitoneum: When Not to Operate

Instrumentation at the leading edge of proteomics

Contact Info

Product

Resources

About