Diffuse Neonatal Hemangiomatosis with Severe Gastrointestinal Involvement

Stillman, Alfred E.; Hansen, Ronald C.; Hallinan, Virginia; Strobel, Cory T.

doi:10.1177/000992288302200817

Cited by 37 publications

(18 citation statements)

References 10 publications

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“…Based on endoscopy and left gastric angiography (late filling phenomenon) findings, the lesion was identified as a gastric hemangioma. Angiography is helpful in demonstrating the arterial supply to the tumor and is the method of choice for confirming the diagnosis [6]. …”

Section: Discussionmentioning

confidence: 99%

Gastric Hemangioma Treated with Argon Plasma Coagulation in a Newborn Infant

Lee¹,

Chun

Hwang

et al. 2017

Pediatr Gastroenterol Hepatol Nutr

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Gastric hemangioma in the neonatal period is a very rare cause of upper gastrointestinal bleeding. We present a case of hemangioma limited to the gastric cavity in a 10-day-old infant. A huge, erythematous mass with bleeding was observed on the lesser curvature side of the upper part of the stomach. Surgical resection was ruled out because the location of the lesion was too close to the gastroesophageal junction. Medical treatment with intravenous H2 blockers, octreotide, packed red blood cell infusions, local epinephrine injection at the lesion site, application of hemoclip, and gel-form embolization of the left gastric artery did not significantly alter the transfusion requirement. Hemostasis was achieved with endoscopic argon plasma coagulation (APC). After two sessions of APC, complete removal of the lesion was achieved. APC was a simple, safe and effective tool for hemostasis and the ablation of gastric hemangioma without significant complications.

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Section: Discussionmentioning

confidence: 99%

Gastric Hemangioma Treated with Argon Plasma Coagulation in a Newborn Infant

Lee¹,

Chun

Hwang

et al. 2017

Pediatr Gastroenterol Hepatol Nutr

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“…MRI is also useful but is unlikely to contribute to the specific diagnosis. Angiography delineates the arterial supply of the tumor and is useful for confirming the diagnosis [9]. Angiography-directed embolization may also be beneficial in cases of acute bleeding.…”

Section: Discussionmentioning

confidence: 99%

Isolated Cavernous Hemangioma: A Rare Benign Lesion of the Stomach

et al. 2012

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Gastric cavernous hemangioma is a relatively rare benign gastric disease. Here we report the case of a 25-year-old male patient who had been admitted complaining of epigastric pain and hematemesis. Preoperative imaging indicated that the mass lesion palpated in the epigastric region was a probable mesenchymal tumor of gastric origin. Due to the hypervascular nature and submucosal localization of the mass, we did not obtain definitive preoperative diagnosis by endoscopic biopsy. The histologic diagnosis of cavernous hemangioma was confirmed by post-resection histopathologial evaluation of the mass.

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“…It is usually apparent at birth or soon after, but may not present with medical complications until several months of age when the lesions undergo an accelerated growth phase [6]. Although the individual lesions are histologically benign, the clinical outcome in patients who do not receive treatment is extremely poor with high mortality rates [1,2,6,7,13]. Since the conditions may appear identical at birth, it is therefore very important to differentiate this from the more common multiple cutaneous haemangiomatosis in which the internal organs are spared.…”

Section: Discussionmentioning

confidence: 99%

“…Diffuse infantile haemangiomatosis is a rare condition characterised by multiple haemangiomas of the skin and viscera [1,2,6,7,13]. In spite of its benign histological appearance there is high morbidity and mortality [2,6,7,13].…”

Section: Introductionmentioning

confidence: 99%

“…In spite of its benign histological appearance there is high morbidity and mortality [2,6,7,13]. Death usually results from high-output cardiac failure due to arteriovenous shunting through the lesions, or to haemorrhage from fragile vessels exacerbated by thrombocytopenia [13]. Five patients are described demonstrating the diverse clinicopathological features and management problems presented by such cases, which differ greatly from those of multiple cutaneous haemangiomatosis.…”

Section: Introductionmentioning

confidence: 99%

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Diffuse infantile haemangiomatosis: clinicopathological features and management problems in five fatal cases

et al. 1991

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The clinicopathological features of five fatal cases of diffuse haemangiomatosis presenting in neonatal life or early infancy are presented. The infants all had multiple skin haemangiomas as well as deep-seated lesions in many different tissues that caused protean clinical manifestations and management problems. Because the outlook may be improved by early diagnosis and application of new modes of treatment, any infant with multiple cutaneous haemangiomas should be closely assessed for possible visceral involvement. Development of hepatomegaly, high-output cardiac failure, unexplained anaemia or thrombocytopenia in these infants should immediately suggest disseminated disease. Early recognition with implementation of steroid and/or antiangiogenic therapy, embolization and/or surgery is essential to improve the chances of survival.

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Diffuse Neonatal Hemangiomatosis with Severe Gastrointestinal Involvement

Cited by 37 publications

References 10 publications

Gastric Hemangioma Treated with Argon Plasma Coagulation in a Newborn Infant

Gastric Hemangioma Treated with Argon Plasma Coagulation in a Newborn Infant

Isolated Cavernous Hemangioma: A Rare Benign Lesion of the Stomach

Diffuse infantile haemangiomatosis: clinicopathological features and management problems in five fatal cases

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