Diffuse large B‐cell lymphoma mimicking cardiac amyloidosis

Cardiac tumors are rare and benign masses account for the most part of the diagnosis. When malignant cancer is detected, primary or secondary cardiac lymphoma are quite frequent. Cardiac lymphoma may present as an intra or peri-cardiac mass or, rarely, it may diffusely infiltrate the myocardium. Although often asymptomatic, patients can have non-specific symptoms. Acute presentations with cardiogenic shock, unstable angina, or acute myocardial infarction are also described. Modern imaging techniques can help the clinicians not only in the diagnostic phase but also during administration of chemotherapy. A multidisciplinary counseling and serial multi-parametric assessment (echocardiography, cardiac troponin) seem to be the most effective approach to prevent possible fatal complications (i.e., cardiac rupture). Currently, only chemo- and radiotherapy are available options for treatment, but the prognosis remains poor. This is a case of secondary cardiac lymphoma presenting as a mediastinal mass with large infiltration of the heart and the great vessels with a good improvement after only one cycle of chemotherapy. It demonstrates the importance of an early diagnosis to modify the natural history of the disease.

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“… 8 Some case reports showed uncommon presentations like massive cardiac infiltration mimicking restrictive cardiomyopathy. 6 , 8 – 10 …”

Section: Discussionmentioning

confidence: 99%

“…Only other few case reports displayed similar findings, with a recall to infiltrative-hypertrophic cardiomyopathy. 6 , 9 , 10 …”

Section: Discussionmentioning

confidence: 99%

Cardiac lymphoma with early response to chemotherapy: A case report and review of the literature

Bonelli

París

Bisegna

et al. 2022

Journal of Nuclear Cardiology

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Diffuse large B‐cell lymphoma mimicking cardiac amyloidosis

Cited by 1 publication

References 3 publications

Cardiac lymphoma with early response to chemotherapy: A case report and review of the literature

Cardiac lymphoma with early response to chemotherapy: A case report and review of the literature

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