2014
DOI: 10.26444/jpccr/71460
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Diffuse large B cell lymphoma of the oral cavity – Case report

Abstract: The study presents an atypical location of Non-Hodgkin lymphoma of the oral cavity in the area of the palate. Pathological changes of the mucosa of the palate in an 85-year-old female patient had been developing for many years as a result of upper denture irritation without any major symptoms. Histological examination revealed a Diffuse large B cell lymphoma. Due to being advanced in years, the patient was qualified for the local radiotherapy. In this particular case, the clinical picture of lymphoma imitated … Show more

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Cited by 3 publications
(6 citation statements)
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“…[ 11 13 ] HLs involve the lymph nodes predominantly and only approximately 5% arise in extranodal sites, whereas 30% of NHLs present in extranodal sites. [ 11 13 14 ] Marginal-zone lymphoma has an affinity for ocular adnexa, salivary glands, larynx and thyroid gland. DLBCL in the oral cavity is considered to be a high-grade lymphoma.…”
Section: Discussionmentioning
confidence: 99%
“…[ 11 13 ] HLs involve the lymph nodes predominantly and only approximately 5% arise in extranodal sites, whereas 30% of NHLs present in extranodal sites. [ 11 13 14 ] Marginal-zone lymphoma has an affinity for ocular adnexa, salivary glands, larynx and thyroid gland. DLBCL in the oral cavity is considered to be a high-grade lymphoma.…”
Section: Discussionmentioning
confidence: 99%
“…The predominance of DLBCL has been explained in the oral cavity as a natural inclination for this site (1,2,5,15). In the oral cavity, DLBCL has been reported in several regions such as buccal mucosa, hard palate, gingiva, and in addition, maxillary vestibule was a characteristic site for the presence of tumors of the soft tissue (1,6). In literature, the primary intrabony region of DLBCL is rare and has been expressed in both the maxilla and mandible (6)(7)(8).…”
Section: Discussionmentioning
confidence: 99%
“…In the oral cavity, DLBCL has been reported in several regions such as buccal mucosa, hard palate, gingiva, and in addition, maxillary vestibule was a characteristic site for the presence of tumors of the soft tissue (1,6). In literature, the primary intrabony region of DLBCL is rare and has been expressed in both the maxilla and mandible (6)(7)(8). For DLBCL, the most characteristic symptoms are pain (55%), swelling of the jaw (58%), and mental dysesthesias (20%).…”
Section: Discussionmentioning
confidence: 99%
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“…Immunohistochemistry is necessary to differentiate between benign lymphoid hyperplasia and lymphomatous lesion (9) as well as identifying the subtype of lymphoma.Lymphomas are usually submucosal as compared to squamous cell carcinoma which apprears ulcerative. Other differential diagnosis than oral cavity squamous cell carcinoma includes benign lymphoid hyperplasia, epulis, gingivitis, pregnancy granuloma, vascular-angio granuloma, HIV-related oral lesion and tuberculosis should be considered (10).…”
Section: Case Reportmentioning
confidence: 99%