2022
DOI: 10.3390/curroncol29090480
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Diffuse Large B Cell Lymphoma Arising in Patients with Preexisting Hodgkin Lymphoma

Abstract: The metachronic onset of diffuse large B-cell lymphoma (DLBCL) after classic Hodgkin lymphoma (cHL) is a rare event affecting patients’ outcomes. However, although several studies have investigated the prognostic role of this event, little is known about a hypothetical common origin of the two different neoplastic cells. Aims: To investigate a possible relationship between DLBCL and cHL, in this retrospective study of 269 patients with newly diagnosed cHL treated at Bari University Hospital (Italy) between 200… Show more

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“…Although the incidence of NHL was significantly decreased in the highly active antiretroviral treatment (HAART) era, HIV-infected patients were at about 500-fold risk of NHL compared to HIV-uninfected patients [ 3 , 4 ]. Importantly, DLBCL is the most common subtype, accounting for 35–60% of all cases of reported NHL [ 5 , 6 ].…”
Section: Introductionmentioning
confidence: 99%
“…Although the incidence of NHL was significantly decreased in the highly active antiretroviral treatment (HAART) era, HIV-infected patients were at about 500-fold risk of NHL compared to HIV-uninfected patients [ 3 , 4 ]. Importantly, DLBCL is the most common subtype, accounting for 35–60% of all cases of reported NHL [ 5 , 6 ].…”
Section: Introductionmentioning
confidence: 99%