“…Dyspnea caused by a large extraluminal osteophytic mass directly compressing, distorting, and finally obstructing the airway with no evidence of associated vocal fold immobility or soft tissue swelling has been reported in 18 cases [5, 6, 8, 12, 14, 16, 18-20, 23, 24, 28-30]. Mechanical irritation of the retrocricoid area caused by rolling over prominent and spiky osteophytes at each swallow resulting in a chronic inflammatory edema obstructing the larynx has been postulated as the cause of dyspnea in five reported cases [2,11,17,21,27]. Similarly, iatrogenic manipulations such as tracheal intubation and respiratory infections may increase tissue inflammation and may complicate moderate symptoms [8,12,19].…”