Diffuse idiopathic fibrosis

Idiopathic subcutaneous and laryngeal fibrosis

“…Although fibrosis was a dominant feature of the laryngeal and subcutaneous masses in the present case, the absence of any evidence of retroperitoneal or mediastinal involvement clinically and radiologically ruled out the possibility of idiopathic multifocal fibrosclerosis (Comings et al, 1967;Parington, 1961;Hamilton and Thiru, 1983). In one reported case of multifocal fibrosclerosis (Coopersmith and Appehnan, 1971), there was associated subcutaneous fibrosis in the abdominal wall in addition to retroperitoneal and mediastinal fibrosis.…”

“…Multiple subcutaneous and submucosal masses of either fibrous or non-fibrous origin, with or without visceral involvement, have been reported in many different conditions, such as neurofibromatosis (Riccardi, 1981), amyloidosis (Michaels and Hyams, 1979; Barnes and Zafar, 1977;Gottschalk and Graham, 1975), Gardner's syndrome (Weary et ai, 1964), multifocal fibrosclerosis (Comings et ai, 1967;Parington, 1961;Hamilton and Thiru, 1983;Coopersmith and Appelman, 1971), and familial multicentric fibromatosis (Zayid and Dihmis, 1969).…”

The effects of steroid therapy on pulmonary hypertension secondary to fibrosing mediastinitis

“…Although confined to the mediastinum, the illness may represent the regional expression of a generalized systemic, sclerosing disease. 13 Reports that support this notion have described an association between fibrosing mediastinitis, retroperitoneal fibrosis, [14][15][16][17][18][19] and other illnesses of a sclerosing nature, including sclerosing cholangitis, Riedel's thyroiditis, orbital pseudotumor, and constrictive pericarditis. [13][14][15][16][17][18][19][20] Certain connective tissue diseases (scleroderma, 21 systemic lupus erythematosus 22 ), vasculitides (polyarteritis nodosa, 23 systemic necrotizing vasculitis 24 ), and drugs (ergotamine, methysergide, hydralazine, and propranolol 25 " 27 ) have been specifically implicated as causes of retroperitoneal fibrosis.…”

Multifocal Fibrosclerosis

“…Pulmonary changes are rare in multifocal fibrosclerosis. Partington (1961) reported a patient with mediastinal and retroperitoneal fibrosis who also had pleural thickening over the lower lobe of the left lung. He had previously been treated for pulmonary tuberculosis.…”