Diffuse hypertrichosis during treatment with 5% topical minoxidil

Peluso, Anna Maria; Misciali, C.; Vincenzi, Colombina; Tosti, Antonella

doi:10.1111/j.1365-2133.1997.tb08760.x

Cited by 59 publications

(17 citation statements)

References 12 publications

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“…Side‐effects of minoxidil treatment include allergic contact dermatitis, which precludes further use of the drug and reversible hypertrichosis. This is usually seen with the 5% concentration 30 and can involve the face, indicating local contamination, or distal regions such as the arms and the buttocks ( Fig. 10), suggesting drug absorption.…”

Section: Managementmentioning

confidence: 99%

Androgenetic alopecia

Tosti

Piraccini

1999

Int J Dermatology

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Section: Managementmentioning

confidence: 99%

Androgenetic alopecia

Tosti

Piraccini

1999

Int J Dermatology

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“…Occasionally it causes scalp irritation which may be severe enough to cause a temporary increase in hair shedding and patients should be warned about this. Hypertrichosis on the face and on more remote sites has been reported, particularly when higher concentrations of minoxidil are used 37 . This resolves if treatment is stopped.…”

Section: Minoxidilmentioning

confidence: 99%

Female pattern hair loss

Birch

Lalla

Messenger

2002

Clinical and Experimental Dermatology

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Female pattern hair loss is a common condition characterized by a diffuse reduction in hair density over the crown and frontal scalp with retention of the frontal hairline. The prevalence increases with advancing age. It has been widely thought to be the female counterpart of male balding and is often referred to as female androgenetic alopecia. However, the role of androgens is not fully established. Scalp hair loss is undoubtedly a feature of hyperandrogenism in women but many women with female pattern hair loss have no other clinical or biochemical evidence of androgen excess. Female pattern hair loss is probably a multifactorial genetically determined trait and it is possible that both androgen-dependent and androgen-independent mechanisms contribute to the phenotype. In managing patients with female pattern hair loss the physician should be aware that the adverse effects on quality of life can be quite severe and do not necessarily correlate with the objective degree of hair loss. The treatment options are currently limited but modest improvements in hair density are achievable in some women.

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“…The topical form reduces alopecia by increasing circulation and follicular DNA synthesis. Topical minoxidil results in localized hair growth, with only 0.5% to 5% of patients reporting generalized hypertrichosis . It is postulated that hypertrichosis results from systemic absorption combined with follicle hypersensitivity.…”

mentioning

confidence: 99%