Diffuse Hair Loss Induced by Sertraline Use

Kıvrak, Yüksel; Yağcı, İbrahim; Üstündağ, Mehmet; Özcan, Halil

doi:10.1155/2015/703453

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…The mechanism of action of isotretinoin that causes hair loss is unknown. Isotretinoin‐related hair loss usually occurs in the first 3 months of treatment 13 . Retinoids cause deterioration in telogen resistance and decreased anagen time, causing diffuse or localized telogen effluvium during treatment 14 .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters

et al. 2021

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Aim Impairment of biotin metabolism with the use of isotretinoin and the mucocutaneous side effects observed in patients using isotretinoin suggests that they are a result of decreased enzyme activity. We aimed to determine the pattern of skin and hair changes in patients with acne receiving isotretinoin and how these changes were affected by biotin added to the treatment. Materials and methods Sixty patients were divided into two groups. Each group contained 30 patients. Groups A and B received 0.5 mg/kg/day isotretinoin, and 10 mg/day biotin supplement was added to Group B. Both groups were evaluated using a digital dermoscope for hair changes and with a DermaLab® Combo device for transepidermal water loss (TEWL), skin retraction, skin hydration, and skin sebum levels at the beginning and end of the fourth month. Results In group B, the anagen hair ratio increased (P = 0.034) and the telogen hair ratio decreased significantly (P = 0.003). Skin sebum and the skin retraction values decreased in both groups. Skin hydration decreased significantly in group A (P = 0.001), but there was no significant decrease in group B (P = 0.43). Conclusion Biotin (10 mg/day) given in addition to isotretinoin treatment decreased telogen and increased anagen hair rates and helped to maintain skin hydration. The use of 10 mg/day biotin can prevent the mucocutaneous adverse effects of isotretinoin treatment.

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Section: Discussionmentioning

confidence: 99%

Evaluation of biophysical skin parameters and hair changes in patients with acne vulgaris treated with isotretinoin, and the effect of biotin use on these parameters

et al. 2021

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“…Antidepressant-induced alopecia is a rare side effect reported in a limited number of drugs such as fluvoxamine, imipramine, mirtazapine, venlafaxine, fluoxetine, and sertraline [17][18][19][20]. But it is difficult to decide whether hair loss is related to these antidepressant use or not and there is no available specific method for the certain diagnosis [21].…”

Section: Discussionmentioning

confidence: 99%

Alopecia associated with agomelatine use: a case report

Gündoğmuş¹,

İspir²,

Karagöz³

et al. 2017

Psychiatry and Clinical Psychopharmacology

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Drug-induced alopecia, characterized by non-scarring hair loss of scalp and body, is a rare side effect of psychotropic drugs. It has previously been reported with the different antidepressant medications, but has not been described with agomelatine. Agomelatine is an antidepressant with a novel mechanism of action and fewer side effects. Here, we report a 31-year-old male patient with diffuse hair loss induced by agomelatine use and improved by discontinuation the drug. Because antidepressant-induced hair loss is relatively rare, many clinicians may not pay attention for this side effect. As far as we know, this is the first published case report of alopecia associated with agomelatine. ARTICLE HISTORY

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