Diffuse correlation spectroscopy towards dynamic topography of blood flow index in deep tissues: A multi-channel system and experiment validation

Xie, Jinbin; He, Xiangdong; Zhang, Limin; Li, Jiao; Qin, Zhuanping; Gao, Feng

doi:10.1016/j.infrared.2020.103298

Cited by 2 publications

(7 citation statements)

References 35 publications

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“…These results coincide with the outcomes of previous studies. 5,23,24,28 However, due to the long measurement time (192 s), the reconstructed images of baseline and relaxed states are almost identical. Therefore, the direct reconstructed BFI is used to display reconstructed images before and after the cuff occlusion.…”

Section: Cuff Occlusion Test Resultsmentioning

confidence: 99%

“…This makes sense and is consistent with previous DCS arm cuff occlusion experiments. 5 This system can also be implied to monitor thrombotic therapeutic processing on the basis of blood flow detection, and to evaluate microvascular stress response based on hyperemia reaction time.…”

Section: Discussionmentioning

confidence: 99%

“…Real-time monitoring of the tissue blood flow index (BFI) would assist early detection and therapeutic assessment of the relevant diseases. [1][2][3][4][5] Currently, the clinical technologies available for BFI detection, such as, the ultrasound Doppler (limited to larger vessels), the laser Doppler and laser speckle imaging (limited to lower penetration depth), and the perfusion magnetic resonance imaging-MRI (limited to heavy and expensive equipment). In recent years, a dynamic near-infrared spectroscopy (NIRS) technology, namely, diffuse correlation spectroscopy (DCS), has been rapidly developed.…”

Section: Introductionmentioning

confidence: 99%

“…Many diseases are accompanied by abnormal tissues’ blood flow at microvascular level. Real‐time monitoring of the tissue blood flow index (BFI) would assist early detection and therapeutic assessment of the relevant diseases 1–5 . Currently, the clinical technologies available for BFI detection, such as, the ultrasound Doppler (limited to larger vessels), the laser Doppler and laser speckle imaging (limited to lower penetration depth), and the perfusion magnetic resonance imaging‐MRI (limited to heavy and expensive equipment).…”

Section: Introductionmentioning

confidence: 99%

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An extensive upgrading of contact diffuse CorrelationTomography system

Zhang,

Ding,

Shang

et al. 2024

Int J Imaging Syst Tech

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Diffuse correlation tomography (DCT) is an emerging tissue blood flow index (BFI) imaging technique that typically requires a large number of source‐detector pairs, resulting in high instrumentation costs. We developed a low‐cost paradigm for upgrading the DCT system with time‐sharing hardware sensors via optical switches, wherein the S‐D configuration was spatially optimized and combined with a novelty Nth‐order linear algorithm for image reconstruction. We verified this system through the phantom experiment and the lower limb skeletal muscle cuff occlusion test. The reconstructed BFI images exhibit the excellent performance of the upgraded DCT system in retrieval of the target location, outline, and anomaly contrast. For the deepest quasi‐solid anomaly, location accuracy was 90% with the αDB‐contrast of 0.75. While, for the deepest liquid tube anomaly, a good linear relationship was achieved between contrast and pump speed, with the αDB‐contrast of 3.29 at 600 mL/h. For human experiments, it was found that the BFI in the relaxed state was ten times higher than in the cuff occlusion state. This study demonstrates the feasibility of the proposed upgraded low‐cost DCT system for diagnosing various diseases associated with local perfusion abnormalities.

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Section: Cuff Occlusion Test Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

An extensive upgrading of contact diffuse CorrelationTomography system

Zhang,

Ding,

Shang

et al. 2024

Int J Imaging Syst Tech

View full text Add to dashboard Cite

show abstract

“…The decay rate of this curve is a good indicator of flow speed. From DCS measurements, it is necessary to extract the speed by calculating the electric field temporal autocorrelation function G 1 (r, τ) [22], as follows:…”

Section: Theoretical Backgroundmentioning

confidence: 99%

In Vivo Pulse Wave Measurement Through a Multimode Fiber Diffuse Speckle Analysis System

et al. 2021

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Continuous monitoring of in vivo pulsatile blood flow and pulse wave velocity (PWV) is important for clinical applications. These parameters are correlated with physiological parameters, such as blood pressure and elasticity of blood vessels. A multimode fiber diffuse speckle contrast analysis (MMF-DSCA) system was developed for fast measurement of in vivo pulsatile blood flow and pulse wave velocity. With MMF and CCD sensor, the diffuse speckle could be captured and processed with higher temporal resolution of 3 ms. We also induced for the first time an MMF-DSCA for evaluation of PWV, which allows estimation of the blood pressure continuously. To validate its performance, both phantom and in vivo experiments were conducted. The results demonstrate that MMF-DSCA could achieve fast pulsatile blood flow measurement with detailed information of the pulse wave profile and velocity. Taking the advantages of being simple and cost-effective, the flexible system can be easily adapted for continuous monitoring of vital biosigns, such as heart rate, pulse wave, and blood pressure.

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Diffuse correlation spectroscopy towards dynamic topography of blood flow index in deep tissues: A multi-channel system and experiment validation

Cited by 2 publications

References 35 publications

An extensive upgrading of contact diffuse CorrelationTomography system

An extensive upgrading of contact diffuse CorrelationTomography system

In Vivo Pulse Wave Measurement Through a Multimode Fiber Diffuse Speckle Analysis System

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