Diffuse Axonal Injury—Incidence and Outcome

Zahirović, Salko; Burazerović, Eldin; Džurlić, Almir; Avdulah, Hasanagic; Ema, Tahto; Haris, Hodzic; Omerhodžić, Ibrahim

doi:10.1055/s-0035-1566414

Cited by 2 publications

(3 citation statements)

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“…The GOS-E was used to assess patients' clinical outcomes 6 months after sustaining head injury in our research group. In literature, mortality after DAI is found to be variable from 30.8% [7] to 62% [16] while in our study, it was 22%. Similar mortality rates were obtained by Vieira et al and Zahirovic et al…”

Section: Discussioncontrasting

confidence: 52%

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Diffuse axonal injury: Epidemiology, associated risk factors and outcome: An institutional study from teritairy care centre in central India

Jatav¹,

Rege²,

Varma³

et al. 2021

Int. J. Surg. Sci.

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The aim of this study was to describe the outcome of patients with primary diagnosis of DAI and to identify clinical and sociodemographic factors associated with mortality and functional capacity 6 months after the injury. Materials and Methods: A total of 100 adult patients admitted in the department of neurosurgery between September 2019 and March 2021 with mild, moderate and severe traumatic brain injury (GCS ≤ 12) diagnosed to have DAI on CT and MRI, were included in this study. Patients were tracked for up to 6 months following discharge and their outcomes were graded as satisfactory or unsatisfactory using the Glasgow Outcome Scale Extended (GOS-E). Results: Most of the patients with Grade 1 DAI had satisfactory outcome at end of 6 months and most of Grade 3 Dai patients expired within 6 months post injury. Conclusion:The results of our study show that the outcome of DAI patients is determined by the severity of traumatic brain injury and the grade of DAI and is unaffected by patients age, gender, or TBI modality.

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Section: Discussioncontrasting

confidence: 52%

“…in their published trials, with death rates of 30.8% and 25.4%, respectively [7,16] . We also discovered that 48% of our patients had a satisfactory outcome on the GOS-E, whereas 30% failed to improve on 6 month follow-up and remained in the group of unsatisfactory outcome.…”

Section: Discussionmentioning

confidence: 99%

Diffuse axonal injury: Epidemiology, associated risk factors and outcome: An institutional study from teritairy care centre in central India

Jatav¹,

Rege²,

Varma³

et al. 2021

Int. J. Surg. Sci.

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“…in their published trials, with death rates of 30.8% and 25.4%, respectively. [ 7 , 16 ] We also discovered that 48.1% of our patients had a satisfactory outcome on the GOS-E, whereas 26.3% failed to improve on 3-month follow-up and remained in the group of unsatisfactory outcome.…”

Section: Discussionsupporting

confidence: 53%

Outcome of diffuse axonal injury in moderate and severe traumatic brain injury

Javeed¹,

Rehman²,

Afzal³

et al. 2021

Surgical Neurology International

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Background: Diffuse axonal injury (DAI) is a common presentation in neurotrauma. Prognosis is variable but can be dependent on the initial presentation of the patient. In our study, we evaluated the outcome of diffuse axonal injury. Methods: This study was conducted at a tertiary care center from September 2018 to December 2019 and included 133 adult patients with moderate or severe head injury (GCS ≤ 12) diagnosed to have the DAI on the basis of MRI. At 3 months, the result was assessed using the Extended Glasgow Outcome Scale (GOS-E). Results: There were a total of 97 (72.9%) males and 36 (27.1%) females with an average age of 32.4 ± 10 years with a mean GCS of 9 at admission. The most common mode of head trauma was road traffic accidents (RTAs) in 51.9% of patients followed by fall from height in 27.1%. Most patients were admitted with moderate traumatic brain injury (64.7%) and suffered Grade I diffuse axonal injury (41.4%). The average hospital stay was 9 days but majority of patients stayed in hospital for ≤ 11 days. At 3 months, mortality rate was 25.6% and satisfactory outcome observed in 48.1% of patients. The highest mortality was observed in the Grade III DAI. Conclusion: We conclude that the severity of the traumatic head injury and the grade of the DAI impact the outcome. Survivors require long-term hospitalization and rehabilitation to improve their chances of recovery.

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Diffuse Axonal Injury—Incidence and Outcome

Cited by 2 publications

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Diffuse axonal injury: Epidemiology, associated risk factors and outcome: An institutional study from teritairy care centre in central India

Diffuse axonal injury: Epidemiology, associated risk factors and outcome: An institutional study from teritairy care centre in central India

Outcome of diffuse axonal injury in moderate and severe traumatic brain injury

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