Abstract:Abstract. Eight chronic myeloid leukemia (CML) patients ineligible for allogeneic bone m w transplantation (BMT) were intensively treated by a myeloablative chemotherapy identical to the treatment that we use in acute myeloid leukemia (AML).The objectives of such an intensive treatment were both to reduce the size of tbe leukemia stem cell mass as much as possible and subsequently to allow a better mobilization of the residual Ph-negative (Ph-) stem cells. Cytogenetic analyses were systematically performed on … Show more
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