Differenzialdiagnostische Abgrenzung Enzephalitis versus Gliom mittels Magnetresonanzspektroskopie

Parbel, S; Vlaho, S; Gebhardt, B; Porto, Luciana; Hattingen, Elke; Klingebiel, Thomas; Böhles, Hansjosef; Kieslich, Matthias

doi:10.1055/s-2006-933521

Cited by 4 publications

(2 citation statements)

References 6 publications

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“…Most often, they are attributable to inflammatory entities. Also, neoplastic brainstem lesions can present with AP syndrome 8, 9, 10, 11. In addition, AP syndrome can be caused by irritation of the CTZ at the molecular level which does not necessarily show up in lesions detected by magnetic resonance imaging (MRI) as known from drug‐induced AP syndrome 3.…”

Section: Introductionmentioning

confidence: 99%

Area postrema syndrome as frequent feature of Bickerstaff brainstem encephalitis

Zeiner

Brandhofe

Müller–Eschner

et al. 2018

Ann Clin Transl Neurol

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ObjectiveArea postrema (AP) syndrome (defined as: nausea and/or emesis and/or singultus at onset of brainstem dysfunction) comprises complex pathophysiologic mechanisms triggered by different entities. The first objective was to assess the frequency of AP syndrome as a clinical feature in brainstem encephalitis (BE). Finding an especially high prevalence of AP syndrome in Bickerstaff brainstem encephalitis (BBE), we also analyzed the frequency of AP syndrome in other autoimmune diseases with anti‐ganglioside antibodies (Guillain–Barré syndrome (GBS) and its variants).MethodsWe systematically evaluated the prevalence of AP syndrome in BE in all patients treated at our university hospital during a 15‐year period. In a second step, BBE patients were compared to GBS and Miller Fisher syndrome (MFS) patients as clinical subtypes of a disease continuum without brainstem dysfunction.ResultsWe found AP syndrome in 8 of 21 BE patients, including 3 of 7 BBE and in 4 of 112 GBS/MFS patients. AP syndrome was as a frequent but under‐recognized feature of BE with a significant impact on patients’ well being.InterpretationManifestation of AP syndrome in BBE but also in GBS and its subtypes point toward a role of autoimmune antibodies that should be investigated in future studies. Considerable misdiagnosis or nonrecognition complicates diagnostic and therapeutic management. Therefore, AP syndrome should be considered in any episode of otherwise unexplained nausea, emesis, or singultus.

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Section: Introductionmentioning

confidence: 99%

Area postrema syndrome as frequent feature of Bickerstaff brainstem encephalitis

Zeiner

Brandhofe

Müller–Eschner

et al. 2018

Ann Clin Transl Neurol

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“…Im MRT des Sch ä dels fallen h ä ufi g -wie bei unserem Patienten -beidseitige Papillen ö deme und eine leichte Kompression der Hypophyse ("empty sella") auf [2] . Wenn mittels MRT nicht sicher zwischen diffus infi ltrierenden gliomat ö sen Tumoren und entz ü ndlichen ZNS-L ä sionen unterschieden werden kann, ist eine Magnetresonanzspektroskopie hilfreich [5] . Der Liquorer ö ffnungsdruck sollte bei normalgewichtigen Patienten < 20 cm und bei adip ö sen Patienten < 25 cm Wassers ä ule betragen [8] .…”

Section: Diagnostikunclassified

Kopfschmerzen und Doppelbilder bei einem Jugendlichen mit extremer Adipositas

Sousa¹,

Baatz²,

Aksu³

et al. 2008

Klin Padiatr

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Microbiota and glioma: a new perspective from association to clinical translation

Wang,

Ou,

Huang

et al. 2024

Gut Microbes

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Differenzialdiagnostische Abgrenzung Enzephalitis versus Gliom mittels Magnetresonanzspektroskopie

Abstract: This case report shows that cerebral glioma can mimick infective brain disease and that MR-spectroscopy is an important non-invasive tool in this differential diagnosis.

Cited by 4 publications

References 6 publications

Area postrema syndrome as frequent feature of Bickerstaff brainstem encephalitis

Area postrema syndrome as frequent feature of Bickerstaff brainstem encephalitis

Kopfschmerzen und Doppelbilder bei einem Jugendlichen mit extremer Adipositas

Microbiota and glioma: a new perspective from association to clinical translation

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