Differentiation of Medullary and Neuromuscular Effects of Nerve Agents

Rickett, D. L.; Beers, Everette T.

doi:10.1007/978-1-4684-5266-2_42

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1998

2023

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Cited by 4 publications

(2 citation statements)

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“…The apnoea may be mediated through the central nervous system although peripheral factors like bronchoconstriction or intercostal muscle weakness may contribute. 1,14,15…”

Section: Airwaysmentioning

confidence: 99%

A Review Article on Nerve Agents

Tang¹,

Chan²

2002

Hong Kong Journal of Emergency Medicine

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The incidence of Tokyo subway attack by the Aum Shinrikyo cult in 1995 had raised the concern of the use of nerve agent as a weapon in terrorist attack. The recent event in World Trade Centre in New York city had further brought our attention to the possibility of terrorist attacks using these agents. In view of the high possibility of nerve agents being used as chemical weapon, medical personnel should have a clear knowledge of these agents. This article aim to provide a detailed discussion of these agents.

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“…The apnoea may be mediated through the central nervous system although peripheral factors like bronchoconstriction or intercostal muscle weakness may contribute. 1,14,15…”

Section: Airwaysmentioning

confidence: 99%

A Review Article on Nerve Agents

Tang¹,

Chan²

2002

Hong Kong Journal of Emergency Medicine

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show abstract

“…6 The half lethal dose (LD 50 ) values of soman in intravenous administration were reported to be 4, 10, 15, and 35 mg kg −1 in rats, dogs, cats, and mice, respectively. [7][8][9][10] In 6 dpf zebrash larvae, the calculated LC 50 -24 h values of soman were reported to be 21.8, 4.0, 2.3, and 1.3 mM following exposure times of 30, 60, 90, and 120 min, respectively. 11 To the best of our knowledge, the toxicity of PMPA is little reported, especially in animals.…”

Section: Introductionmentioning

confidence: 99%