Abstract:The differentiation of dendritic cells (DCs) in vitro is not yet under full control and although PPAR-γ stimulation may interfere with DC differentiation from cord blood progenitors, the expression of PPAR-γ by different precursors and the effect of PPAR-γ stimulation on DC differentiation are poorly known. To address these issues, CD14+ monocytes, CD34+ progenitors and CD133+ progenitors were isolated from adult healthy donors and cultured with cytokines; rosiglitazone (1 µmol/l) was used to stimulate PPAR-γ.… Show more
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