Differentiating multiple vs single lifetime suicide attempters with bipolar disorders: A retrospective study

Arici, C.; Cremaschi, Laura; Dobrea, Cristina; Vismara, Matteo; Grancini, Benedetta; Benatti, Beatrice; Buoli, Massimiliano; Miller, Shefali; Ketter, Terence A.; Altamura, Alfredo Carlo; Dell’Osso, Bernardo

doi:10.1016/j.comppsych.2017.10.006

Cited by 15 publications

(17 citation statements)

References 43 publications

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“…Suicide attempters had a higher rate of personality disorders than controls with no suicide risk. This finding is in line with previously published studies (15,37) reporting an association between repeat suicidal behaviors and personality disorders, mainly borderline personality disorder. Of note is the fact that the proximal risk factor may play an important role in the precipitation of suicide (38).…”

Section: Discussionsupporting

confidence: 93%

“…Previous studies also investigated clinical differences between SSAs and MSAs, focusing on patients sharing the same psychiatric diagnosis (6,15). Boisseau et al (32) found that Axis I disorders were not predictive of repeat suicidal behavior in a 10year follow-up study.…”

Section: Discussionmentioning

confidence: 99%

“…As compared to SSAs, MSAs had significantly higher motor impulsivity, indicating spur-of-the-moment action (13,14). MSAs also had a longer duration of bipolar illness, more frequently lived alone, had more than one psychiatric comorbidity, and were more likely to attempt suicide by self-poisoning (although this is also the most common suicide method in SSAs) (15). MSAs and SSAs presented higher levels of depression, hopelessness, aggression, hostility, impulsivity, borderline personality traits, and family history of major depression or alcohol use disorder as compared to psychiatric patients who were non-attempters (16).…”

Section: Introductionmentioning

confidence: 99%

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Clinical Differences Between Single and Multiple Suicide Attempters, Suicide Ideators, and Non-suicidal Inpatients

et al. 2020

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Single suicide attempters (SSAs) and multiple suicide attempters (MSAs) represent distinct subgroups of individuals with specific risk factors and clinical characteristics. This retrospective study on a sample of 397 adult psychiatric inpatients analyzed the main sociodemographic and clinical differences between SSAs and MSAs and the possible differences between SSAs, MSAs, and psychiatric patients with and without suicidal ideation (SI). Clinical variables collected included psychiatric diagnoses (Mini International Neuropsychiatric Interview), presence of substance use, current suicide risk status (Columbia Suicide Severity Rating Scale), Clinical Global Impression at admission, Global Assessment of Functioning improvement between admission and discharge, age at onset of psychiatric illness, duration of untreated illness in years, number of hospitalizations in psychiatric settings, and lethality of the most severe suicide attempt. A multinomial logistic regression model with groups showed that MSAs had a higher lethality of their last suicide attempt as compared to SSAs. In addition, MSAs had distinct sociodemographic characteristics compared to both SSAs and patients with SI. Although the study was limited by the relatively small sample size and retrospective nature, the present results suggest that identifying MSAs could be useful in predicting suicide risk and designing ad hoc prevention strategies.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinical Differences Between Single and Multiple Suicide Attempters, Suicide Ideators, and Non-suicidal Inpatients

et al. 2020

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“…BD has a tremendous impact on patients' and caregivers' lives and it has been associated with high rates of divorces and volatility of social relationships [5]. Clinical management of patients with BD can be challenging in light of frequent juvenile onset [6], misdiagnosis with other psychiatric diagnoses (especially major depression and psychotic disorders) [7] and high suicidal risk [8].…”

Section: Introductionmentioning

confidence: 99%

Correlates of current rapid-cycling bipolar disorder: Results from the Italian multicentric RENDiBi study

et al. 2019

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Background: we aimed to compare socio-demographic and clinical differences between patients with versus without current RC in order to detect clinical factors that may favor early diagnosis and personalized treatment. Methods: A total of 1675 patients (males: n = 714 and females: n = 961; bipolar 1: n = 1042 and bipolar 2: n = 633) from different psychiatric clinics were grouped and compared according to the current presence of RC in terms of socio-demographic and clinical variables. Chi-squared tests for qualitative variables and Student’s t tests for quantitative variables were executed for group comparison, and multivariable logistic regressions were performed, considering the current presence of RC as dependent variable, and socio-demographic/clinical factors as independent variables. Results: Female gender (male versus female: OR = 0.64, p = 0.04), unidentifiable prevalent polarity (versus depressive polarity: OR = 1.76, p = 0.02; versus manic polarity: OR: 2.86, p < 0.01) and hospitalization in the last year (no versus yes: OR = 0.63, p = 0.02) were found to be associated with RC in the final multivariable regression analysis. Conclusions: RC in BD seems to be more prevalent in female gender and associated with some unfavorable clinical features, such as an increased risk of hospitalization. These aspects should be taken into account in the management and monitoring of RC versus non-RC patients.

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“…SUDs were not associated with the presence vs. absence of previous SA, however, the study lacked statistical power (N=52). The second (Arici et al, 2018) identified psychiatric comorbidity and living alone as specific risk factors for recurrent SA, in a larger sample (N=362, including 95 suicide attempters). The most frequent comorbidity pattern associated with recurrent SA was 'anxiety + SUD', but separate results for SUDs were not reported.…”

Section: Introductionmentioning

confidence: 99%

Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder

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et al. 2019

Journal of Affective Disorders

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HAL is a multi-disciplinary open access archive for the deposit and dissemination of scientific research documents, whether they are published or not. The documents may come from teaching and research institutions in France or abroad, or from public or private research centers. L'archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d'enseignement et de recherche français ou étrangers, des laboratoires publics ou privés.

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Differentiating multiple vs single lifetime suicide attempters with bipolar disorders: A retrospective study

Cited by 15 publications

References 43 publications

Clinical Differences Between Single and Multiple Suicide Attempters, Suicide Ideators, and Non-suicidal Inpatients

Clinical Differences Between Single and Multiple Suicide Attempters, Suicide Ideators, and Non-suicidal Inpatients

Correlates of current rapid-cycling bipolar disorder: Results from the Italian multicentric RENDiBi study

Tobacco smoking and other substance use disorders associated with recurrent suicide attempts in bipolar disorder

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