Differentiating bipolar disorder in Turkish prepubertal children with attention‐deficit hyperactivity disorder

Diler, Rasim Somer; Uğuz, Şükrü; Seydaoğlu, Gülşah; Erol, Neşe; Avcı, Ayşe

doi:10.1111/j.1399-5618.2007.00347.x

Cited by 31 publications

(32 citation statements)

References 61 publications

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“…A Brazilian sample ascertained from a chart review of patients under 15 found that those CBCL subscales that showed differences between those diagnosed with JBD and those diagnosed with ADHD were the Anxious/Depressed, Delinquent Problems, and Aggressive Behavior subscales (Tramontina et al, 2003). Diler and colleagues (2007) found that their ADHD+JBD group was different from an ADHD group on the Anxious/Depressed, Social Problems, Thought Problems, and Aggression subscales. Thus, although elevations on the CBCL are common findings in JBD research, the specificity is questionable.…”

Section: Introductionmentioning

confidence: 88%

Childhood CBCL bipolar profile and adolescent/young adult personality disorders: A 9-year follow-up

Halperin

Rucklidge

Powers

et al. 2011

Journal of Affective Disorders

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Section: Introductionmentioning

confidence: 88%

Childhood CBCL bipolar profile and adolescent/young adult personality disorders: A 9-year follow-up

Halperin

Rucklidge

Powers

et al. 2011

Journal of Affective Disorders

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“…Examining the course of BD, adults with ''BD ? ADHD'' were characterized by an earlier age of disease onset (compared to ''BD-ADHD''), a more severe course of disorder with shorter periods of well-being, a higher number of affective episodes, and higher comorbidity rates with other psychiatric disorders (Nierenberg et al 2005;Tamam et al 2006;Wingo and Ghaemi 2007;Diler et al 2007;Rydén et al 2009;Bernardi et al 2010).…”

Section: Bipolar Disorder (Bd)mentioning

confidence: 98%

Developmental comorbidity in attention-deficit/hyperactivity disorder

Taurines

Schmitt

Renner

et al. 2010

ADHD Atten Def Hyp Disord

162

116

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With the present review, we intend to highlight the importance of considering the age- and development-dependent occurrence of comorbidity in ADHD and to outline distinct trajectories of symptom progression with possible impact on course and outcome of ADHD. The review will focus on introducing the concepts of "developmental epidemiology" and "developmental comorbidity". Psychiatric and non-psychiatric age-dependent comorbidity can be seen in the majority of children, adolescents and adults with ADHD, resulting in a severe impairment of everyday life with considerable functional and psychosocial problems. Concerning the temporal order of occurrence, psychiatric conditions may be present before the appearance of first definite ADHD symptoms ("pre-comorbidity", such as temperament factors, sleep disturbance, autism spectrum disorders and atopic eczema). They may coincide with the time when ADHD symptoms reach a clinically significant level ("simultaneous comorbidity": enuresis, encopresis, developmental dyslexia). The majority of comorbidity, however, appears after the onset of ADHD in the course of disease ("post-comorbidity": tic disorder, depression and suicidality, anxiety disorders, obsessive compulsive disorder, bipolar disorder, conduct and substance use disorders, obesity and personality disorders). The aetio-pathophysiology of ADHD and its comorbid disorders and also the nature of comorbidity itself being highly heterogeneous, we additionally discuss possible models of comorbidity. In the future, longitudinal data on distinct patterns of symptom and comorbidity progression would help to refine disease classification systems, strengthen the power of future genetic studies and finally allow for more specific treatment strategies.

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“…Biederman and colleagues (Biederman et al , 1996Faraone et al 2005) reported that youngsters who were diagnosed with bipolar disorder (using a semi-structured diagnostic interview) had clinically significant elevations (T-scores [ 70) on the following CBCL subscales: Aggression, Attention Problems, and Anxious/Depressed. This profile has been replicated by other investigators (e.g., Carlson and Kelly 1998;Diler et al 2007;Giles et al 2007;Hazell et al 1999) and meta-analysis showed that this profile differentiated between youngsters diagnosed with bipolar disorder and those with ADHD (Mick et al 2003).…”

Section: Introductionmentioning

confidence: 61%

The CBCL Bipolar Profile and Attention, Mood, and Behavior Dysregulation

2010

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Biederman and colleagues reported that a CBCL profile identified youngsters who were diagnosed with bipolar disorder. Some studies found that this CBCL profile does not reliably identify children who present with bipolar disorder, but nonetheless this CBCL does identify youngsters with severe dysfunction. However, the nature of the impairment of youngsters who fit this profile is unclear. The goal of this study was to describe the clinical characteristics of youngsters who fit this CBCL profile. The sample included 310 youngsters referred to an outpatient psychopharmacology clinic. There were 55 youngsters who fit the CBCL profile. These youngsters were compared to 255 youngsters who did not fit the CBCL profile. Measures included the CBCL, standardized measures of aggression and ADHD symptoms, youngsters’ self-reported depression, DSM-IV diagnoses, and child and adolescent psychiatrists’ ratings of impairment and functioning. Compared to youngsters who did not fit the CBCL bipolar disorder profile, youngsters who fit the profile had significantly higher scores on all but one CBCL scale and significantly higher levels of aggression. Youngsters who fit the CBCL profile also had greater psychosocial impairment and more DSM-IV diagnoses than youngsters who did not fit the profile. Youngsters who fit the CBCL profile exhibit severe dysregulation across multiple domains of functioning including attention, affective, and behavioral dysregulation that are not easily nor efficiently captured by extant DSM-IV diagnoses. These youngsters are not uncommon and comprise slightly less than 1 in 5 referrals to a child psychiatry clinic

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Differentiating bipolar disorder in Turkish prepubertal children with attention‐deficit hyperactivity disorder

Cited by 31 publications

References 61 publications

Childhood CBCL bipolar profile and adolescent/young adult personality disorders: A 9-year follow-up

Childhood CBCL bipolar profile and adolescent/young adult personality disorders: A 9-year follow-up

Developmental comorbidity in attention-deficit/hyperactivity disorder

The CBCL Bipolar Profile and Attention, Mood, and Behavior Dysregulation

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