Differentiated Approach to Vein Thromboembolic  Complication Prevention in Military Low-Extremity  Firearm Injury

Nikolaev, K. N.; Zubritsky, V. F.; Koltovich, A. P.; Ивченко, Д.Р.; Акимов, А. В.; Голубов, Е. А.; DVORTSEVOY, SERGEY N .; Капустин, С И

doi:10.20969/vskm.2018.11(1).38-44

BCCM

2018

DOI: 10.20969/vskm.2018.11(1).38-44

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Differentiated Approach to Vein Thromboembolic Complication Prevention in Military Low-Extremity Firearm Injury

K. N. Nikolaev¹,

V. F. Zubritsky²,

A. P. Koltovich³

et al.

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Risk Factors of Deep Vein Thrombosis in Combat Gunshot Injury

Salukhov,

Gavrilov,

Varavin

et al. 2024

J. Ven. Disord.

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Risk Factors of Deep Vein Thrombosis in Combat Gunshot Injury

Salukhov,

Gavrilov,

Varavin

et al. 2024

J. Ven. Disord.

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Comparative evaluation of preventive anticoagulant therapy regimens in the wounded

Varavin,

Salukhov,

Kryukov

et al. 2023

Medicinskij sovet

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Aim. To study various modes of anticoagulant therapy for the prevention of venous thrombosis of the lower extremities in the wounded after surgery using the parameters of the plasma hemostasis system and the Thrombodynamics test.Materials and methods. A prospective study was conducted, which included 90 wounded with mine-explosive/gunshot injury receiving anticoagulant therapy in preventive doses. The studies were carried out on the equipment of the Thrombodynamics recorder (HemaCor, Moscow). The patients were divided into 3 groups: 1 group, which included 30 patients taking rivaroxaban at a dose of 10 mg/day, 2 group of 30 patients receiving enoxaparin sodium at a dose of 40 mg once a day, 3 group consisting of 30 patients receiving enoxaparin sodium 40 mg 2 times a day. In the dynamics of treatment, the parameters of the plasma hemostasis system and the parameters of the Thrombodynamics test were evaluated.Results. It was revealed that during preventive anticoagulant therapy, there were no significant differences in the standard parameters of the coagulogram, when studying the parameters of the Thrombodynamics test, significant differences were observed between groups 1 and 3 in values (V/VSt, Vi, Tlag, СS), between group 2 and 3 in parameter (V/VSt, Vi, Tlag, СS), between group 1 and group 2 in the value of D. A statistically significant relationship was found between the Thrombodynamics parameter D and the indicators of TV, prothrombin by Quick, and fibrinogen content.Conclusion. The Thrombodynamics test can be used as a potential tool for a personalized approach to monitoring the hemostasis system in the wounded.

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Differentiated Approach to Vein Thromboembolic Complication Prevention in Military Low-Extremity Firearm Injury

Cited by 2 publications

References 0 publications

Risk Factors of Deep Vein Thrombosis in Combat Gunshot Injury

Risk Factors of Deep Vein Thrombosis in Combat Gunshot Injury

Comparative evaluation of preventive anticoagulant therapy regimens in the wounded

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