Abstract:Lectins are proteins that recognize specific carbohydrates, and the vasorelaxant effect of legume lectins has been previously reported, for example the Dioclea rostrata lectin (DRL). This study evaluated major pathways of DRL‐induced relaxation in different artery segments and the possible molecular interactions involved. Rat thoracic aorta, coronary and mesenteric resistance arteries were tested “in vitro” with concentration‐response curves to DRL (0.01‐100 µg/mL). L‐NAME, indomethacin and high KCl were used … Show more
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