Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses

High yields of influenza A virus in Madin-Darby canine kidney cells are promoted by an insufficient interferon-induced antiviral state

“…This may have prevented the development of influenza-inhibiting properties of canine Mx proteins. Recently, a screen with several cell lines was performed to identify the susceptibility of different cell lines to seasonal influenza A H1N1, swine-origin H1N1 and avian H5N1 (Li et al, 2009). Among all the animal cells tested, MDCK cells best supported the growth of all the influenza viruses.…”

Characteristics of Acute Kidney Injury in Patients Infected with the 2009 Influenza A (H1N1) Virus

“…The authors identified viral RNA in the lung, heart, thymus, liver, spleen, and kidneys. Li et al compared cell lines infected with pandemic H1N1, seasonal H1N1, and avian influenza A (H5N1) in terms of their growth characteristics (12). They found that the H1N1 viruses were able to replicate in hepatic, renal, neural, and monocyte cell lines.…”

Mycophenolic acid, an immunomodulator, has potent and broad-spectrum in vitro antiviral activity against pandemic, seasonal and avian influenza viruses affecting humans

“…All virus strains used in this study were isolated from patients ( Table 1). The virus strains H1/415, H7/ AH1 and H7/ZJ1 were used in our previous studies (Chan et al, 2013b;Chen et al, 2013;Li et al, 2009;Zheng et al, 2008). These viruses were propagated in MDCK cells before use.…”