Differential Survival to Leukemia as a Function of Infantile Stimulation in DBA/2 Mice.

Levine, Seymour; Cohen, Carl

doi:10.3181/00379727-102-25140

Cited by 30 publications

(16 citation statements)

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“…Finally, since this volume is dedicated to the late Seymour (Gig) Levine and his pervasive influence on the field of early experience, it seems fitting to note that the general notion of a link between one’s early experience and later immunological functioning and health was recognized by Gig long ago (Levine & Cohen, 1959; Solomon et al, 1968). While a fuller recognition of the implications of such early findings had to await the interpretative context provided by more-recent results and theory from the field of psychoneuroimmunology, Gig’s ideas and findings here, as in so many other areas, presaged modern trends in developmental and neuroscience research.…”

Section: Conclusion Qualifications and Limitationsmentioning

confidence: 99%

Early attachment-figure separation and increased risk for later depression: Potential mediation by proinflammatory processes

Hennessy

Deak

Schiml-Webb

2010

Neuroscience & Biobehavioral Reviews

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Early maternal separation and other disruptions of attachment relations are known to increase risk for the later onset of depressive illness in vulnerable individuals. It is suggested here that sensitization involving proinflammatory processes may contribute to this effect. This argument is based on: (1) current notions of the role of proinflammatory cytokines in depressive illness; (2) evidence that proinflammatory cytokines mediate depressive-like behavior during separation in a rodent model of infant attachment; and (3) comparisons of the effects of early proinflammatory activation versus maternal separation on later proinflammatory activity and biobehavioral processes related to depression. The possible interaction of proinflammatory processes and corticotropin-releasing factor in the sensitization process is discussed.

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Section: Conclusion Qualifications and Limitationsmentioning

confidence: 99%

Early attachment-figure separation and increased risk for later depression: Potential mediation by proinflammatory processes

Hennessy

Deak

Schiml-Webb

2010

Neuroscience & Biobehavioral Reviews

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“…Both the nature of the stress and the exact time of the stress accounted for a significant variability in the response. In yet another study, stimulation by handling during the first 3 weeks of life has been shown to shorten the survival time of mice after transplantation of lymphoid leukemia as compared to unstimulated mice (51).…”

Section: Stress and Experimental Illnessmentioning

confidence: 99%

The Influence of the Psyche and the Brain on Immunity and Disease Susceptibility: A Critical Review

Rogers

Dubey

Reich

1979

Psychosomatic Medicine

228

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In critically reviewing the sources of evidence connecting psyche and brain with the immune system, the authors include a brief review of current knowledge of the immune system, its interactions with the neuroendocrine system, and other factors influencing its regulation. These include developmental stages, aging, rhythmicity, and a variety of exogenous influences. The need for developing further information about normal base lines is emphasized. Against that background, many sources of data demonstrating connections between the central nervous system and the immune system are presented: indirect evidence from clinical and experimental illnesses involving the immune system, and direct changes in either humoral or cellular immunity after natural or experimental stress, conditioning, hypnosis, and direct brain stimulation. Possible mechanisms are discussed, as well as some important methodological issues for further research.

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“…With respect to the infra-human investigations, it has been reported that stress may either exacerbate (14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29) or inhibit (14,(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40)(41)(42) tumorigenicity. Aside from stress type and social conditions (2,43), two important factors that contribute to these contradictory findings are ability to control stress and chronicity of stress.…”

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confidence: 99%

Adaptation to the Tumor-Enhancing Effects of Stress

Sklar¹,

Bruto²,

Anisman³

1981

Psychosomatic Medicine

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Growth of P815 mastocytoma in syngeneic DBA/2J male mice was evaluated following several stress regimens. Although escapable shock did not enhance tumor growth, an equivalent amount of inescapable shock applied in a yoked paradigm markedly augmented tumor development. If mice received repeated stress sessions on 5-10 consecutive following tumor cell transplantation, the tumor-enhancing effects of an acute session were abrogated. This effect was not due to an antitumor effect exerted by a shock session applied several days after cell transplantation. It seems that the tumorigenic effects of stress are subject to adaptation since stress exposure prior to cell transplantation also inhibited the effects of an acute stress session. The data were discussed in relation to stress-induced neurochemical alterations.

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Differential Survival to Leukemia as a Function of Infantile Stimulation in DBA/2 Mice.

Cited by 30 publications

References 0 publications

Early attachment-figure separation and increased risk for later depression: Potential mediation by proinflammatory processes

Early attachment-figure separation and increased risk for later depression: Potential mediation by proinflammatory processes

The Influence of the Psyche and the Brain on Immunity and Disease Susceptibility: A Critical Review

Adaptation to the Tumor-Enhancing Effects of Stress

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