Differential Spectrophotometric Method for Determination of Cefquinome Sulphate

Shantier, Shaza W.

doi:10.9734/bjpr/2014/5734

Cited by 3 publications

(2 citation statements)

References 10 publications

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“…The absorption is quantified by the Beer-Lambert law, which relates the absorbance to the concentration of the absorbing species. (9,10,11)  Measurement Process: The instrument measures the intensity of light before and after it passes through the sample. The difference in intensity corresponds to the amount of light absorbed by the sample.…”

Section: A Novel Development and Validation Of Differential Spectroph...mentioning

confidence: 99%

A Novel Development and Validation of Differential Spectrophotometric Method for Determination of Domperidone in Tablet Dosage Form

Khant,

Viroja,

Jani

2023

Preprint

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The amount of domperidone in pharmaceutical dose forms was measured using a straightforward, quick, and sensitive differential spectrophotometric approach. The approach is based on the uv- spectra-differentiated caused spectrum changes that occur when the ph of the medium is changed. To determine the amplitude, the absorbance difference between these two maxima was measured and plotted against concentration. With a detection limit of 0.15 g/ml, the calibration curve is linear over the concentration range of 2 to 10 µg/ml (r2 = 0.997) without the common element that comes with the drug interfering, the procedure was effectively applied to the commercial pharmaceutical drug. The outcome when statistically compared to the outcomes of the standard method. The assay of domperidone in pure and tablet dosage form was completed satisfactorily using the suggested procedures. The assay of domperidone in its pure form and in tablet dosage form was successfully conducted using the suggested procedures. Tablet excipients did not cause any interference when tested under the specified assay conditions and wavelengths. Statistics revealed no difference between the data and those acquired using the spectrophotometric approach described in the literature.

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Section: A Novel Development and Validation Of Differential Spectroph...mentioning

confidence: 99%

A Novel Development and Validation of Differential Spectrophotometric Method for Determination of Domperidone in Tablet Dosage Form

Khant,

Viroja,

Jani

2023

Preprint

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“…Therefore, the application of difference spectrophotometry is expected to have the totality of advantages of both derivative spectrophotometry (first, second, etc.) combined with delta spectrophotometry [23].…”

Section: ∆A = ∆Abc (2)mentioning

confidence: 99%

Drug Analysis

Shantier¹

2020

Pharmaceutical Formulation Design - Recent Practices

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Instrumental methods are widely used for the analysis and stability studies of compounds in bulk and pharmaceutical forms. They vary in their sensitivity, techniques and reagents involved. This chapter will overview those different techniques and the application of the analytical methods. It will also describe how to design and develop simple, sensitive and accurate method for routine quality control of specified compound depending on its molecular structure. Quality control and assurance of the analytical process will be discussed. Furthermore, the chapter will describe a number of factors affecting the chemical and physical stability of Pharmaceutical formulations and how to develop stability-indicating methods to qualify and quantify the drug degradation.

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Review on the Characteristic, Properties and Analytical Methods of Cefquinomesulphate: ß-lactam Veterinary Drug

Shantier

2020

IDDT

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Background: Chemotherapy as a science began within the 1st decade of the twentieth century with understanding of the principles of selective toxicity, the particular chemical relationships between microorganism pathogens and medicines, the event of drug resistance, and also the role of combined medical aid. Objectives: This review aims to highlight the characteristics, specifically the pharmacokinetic parameters and the analytical methods reported in literature for the determination of Cefquinome, a fourth generation cephalosporine used to treat Gram-positive and Gram-negative caused infections. Conclusion: Analysis of such drugs, whether used for the treatment of human or animal illness, is essential in understanding the bioavailability and therapeutic control which will ensure their activity and safety.

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Differential Spectrophotometric Method for Determination of Cefquinome Sulphate

Cited by 3 publications

References 10 publications

A Novel Development and Validation of Differential Spectrophotometric Method for Determination of Domperidone in Tablet Dosage Form

A Novel Development and Validation of Differential Spectrophotometric Method for Determination of Domperidone in Tablet Dosage Form

Drug Analysis

Review on the Characteristic, Properties and Analytical Methods of Cefquinomesulphate: ß-lactam Veterinary Drug

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