Differential Reactivity of Neural and Extra-Neural Vasculature

A report of three patients in whom the surgical closure of terminal branches of the external carotid arteries for treatment of migraine resulted in significantly reduced frequency of epileptic attacks

“…[3] In the Asian monkey, there is a similar phenomenon, in that internal carotid blood flow is determined to a certain extent by the tonus in the external carotid tree. [4] Of greater relevance though, is that bilateral external carotid ligations in both man and monkey have been shown to result in an increase in flow through the internal carotid arteries.…”