Differential Predictive Value of Depressive Versus Anxiety Symptoms in the Prediction of 8-Year Mortality After Acute Coronary Syndrome

Doyle, Frank; Conroy, Ronán; McGee, Hannah

doi:10.1097/psy.0b013e318268978e

Cited by 25 publications

(21 citation statements)

References 27 publications

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“…Differential measurement of depression can lead to starkly contrasting results when predicting prognosis (56,57). Reassuringly, sensitivity analyses demonstrated similar effect estimates for all measures, with the exception of anti-depressants.…”

Section: Study Qualitymentioning

confidence: 75%

Systematic Review and Meta-Analysis of the Impact of Depression on Subsequent Smoking Cessation in Patients With Coronary Heart Disease

Doyle

Rohde

Rutkowska

et al. 2014

Psychosomatic Medicine

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Objective:Smoking cessation is crucial for patients with coronary heart disease (CHD), yet depression may impede cessation success. We systematically reviewed the longitudinal association between depression and subsequent smoking cessation in individuals with CHD in order to quantify this effect. Methods:Electronic databases (PsychInfo, PubMed, CINAHL) were searched for prospective studies of CHD patients which measured depression at baseline (scales, diagnostic interview or antidepressant prescription) and reported smoking continuation/cessation at follow-up. Inclusive dates were 1 st January 1990 to 22 nd May 2013. Standardized mean differences (SMD) and associated 95% confidence interval (CI) were estimated using random effects meta-analysis. Sensitivity analysis explored the impact of limiting metaanalysis to studies using different depression measures (validated scales, diagnostic interviews, antidepressant prescription), different durations of follow-up, or higher quality studies. Results:From 1451 citations retrieved, 28 relevant articles were identified. Meta-analysis of all available data from 20 unique datasets found that depressed CHD patients were significantly less likely to quit smoking at follow-up (SMD=-.39, 95% CI -.50 to -.29; I 2 =51.2%, p=.005). Estimates remained largely unchanged for each sensitivity analysis, except for two studies that used antidepressants, which showed a much larger effect (SMD=-.94, -1.38 to -.51; I 2 =57.7%, p=.124).--2 Conclusions:CHD patients with depressive symptoms are significantly less likely to quit smoking than their non-depressed counterparts. This may have implications for cardiovascular prognosis, and CHD smokers may require aggressive depression treatment to enhance their chances of quitting.Keywords: Depression; coronary heart disease; health behaviors; smoking; smoking

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Section: Study Qualitymentioning

confidence: 75%

Systematic Review and Meta-Analysis of the Impact of Depression on Subsequent Smoking Cessation in Patients With Coronary Heart Disease

Doyle

Rohde

Rutkowska

et al. 2014

Psychosomatic Medicine

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“…27 Depression (PHQ-9: mean score 4.4 [SD 4.5]) and anxiety (HADS-A: mean score 4.3 [SD 4.0]) scores were below established cutoffs for clinically significant depression (PHQ-9≥10) or anxiety (HADS-A≥8), and were slightly lower than mean values in other cardiac populations (PHQ-9=4.8; HADS-A=6.8). 44, 45 …”

Section: Resultsmentioning

confidence: 99%

Effects of Optimism and Gratitude on Physical Activity, Biomarkers, and Readmissions After an Acute Coronary Syndrome

Huffman

Beale

Celano

et al. 2016

Circ: Cardiovascular Quality and Outcomes

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Background Positive psychological constructs, such as optimism, are associated with beneficial health outcomes. However, no study has separately examined the effects of multiple positive psychological constructs on behavioral, biological, and clinical outcomes after an acute coronary syndrome (ACS). Accordingly, we aimed to investigate associations of baseline optimism and gratitude with subsequent physical activity, prognostic biomarkers, and cardiac rehospitalizations in post-ACS patients. Methods and Results Participants were enrolled during admission for ACS and underwent assessments at baseline (2 weeks post-ACS) and follow-up (6 months later). Associations between baseline positive psychological constructs and subsequent physical activity/biomarkers were analyzed using multivariable linear regression. Associations between baseline positive constructs and 6-month rehospitalizations were assessed via multivariable Cox regression. Overall, 164 participants enrolled and completed the baseline 2-week assessments. Baseline optimism was significantly associated with greater physical activity at 6 months (n=153; β=102.5; 95% confidence interval [13.6-191.5]; p=.024), controlling for baseline activity and sociodemographic, medical, and negative psychological covariates. Baseline optimism was also associated with lower rates of cardiac readmissions at 6 months (N=164), controlling for age, gender, and medical comorbidity (hazard ratio=.92; 95% confidence interval [.86-.98]; p=.006). There were no significant relationships between optimism and biomarkers. Gratitude was minimally associated with post-ACS outcomes. Conclusions Post-ACS optimism, but not gratitude, was prospectively and independently associated with superior physical activity and fewer cardiac readmissions. Whether interventions that target optimism can successfully increase optimism or improve cardiovascular outcomes in post-ACS patients is not yet known, but can be tested in future studies. Clinical Trial Registration URL: http://www.clinicaltrials.gov. Unique identifier: NCT01709669.

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“…The use of such tools, would help to further develop our understanding of the relationship between specific components of affective disorder and outcomes, such as cardiovascular mortality [48].…”

Section: Discussionmentioning

confidence: 99%

The Hospital Anxiety and Depression Scale: A meta confirmatory factor analysis

Norton

Cosco

Doyle

et al. 2013

Journal of Psychosomatic Research

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343

340

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Differential Predictive Value of Depressive Versus Anxiety Symptoms in the Prediction of 8-Year Mortality After Acute Coronary Syndrome

Cited by 25 publications

References 27 publications

Systematic Review and Meta-Analysis of the Impact of Depression on Subsequent Smoking Cessation in Patients With Coronary Heart Disease

Systematic Review and Meta-Analysis of the Impact of Depression on Subsequent Smoking Cessation in Patients With Coronary Heart Disease

Effects of Optimism and Gratitude on Physical Activity, Biomarkers, and Readmissions After an Acute Coronary Syndrome

The Hospital Anxiety and Depression Scale: A meta confirmatory factor analysis

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