Differential patterning of neuronal, glial and neural progenitor cells on phosphorus-doped and UV irradiated diamond-like carbon

60 years of DLC coatings: Historical highlights and technical review of cathodic arc processes to synthesize various DLC types, and their evolution for industrial applications

“…However, detailed characterizations of the DLC films (surface properties, mechanical properties, stress and others) are often not reported. Biological reactions are extremely sensitive to even slight changes of the DLC surface, as can for example be seen in [297]. There the growth of cortical neurons (nerve cells) was suppressed in areas where the DLC was additionally exposed to UV radiation prior to the biological experiment.…”

Spatially Controlling Neuronal Adhesion and Inflammatory Reactions on Implantable Diamond

“…In addition, we have used stencil-assisted and photochemical patterning techniques to spatially control neural cell growth on DLC [34]. Here, we extend these findings and compare the cell patterning performance of inkjet printing and the programmable and higher resolution technique of laser etching to produce neuronal networks on DLC and boron-doped diamond.…”

Surface modification of biomaterials using plasma immersion ion implantation and deposition

“…Recent study shows that DLC-coated PEEK possesses better surface hardness and elastic modulus, which are much closer to cortical bones, indicating a possible way to alleviate osteanabrosis caused by stress shielding effects [78]. Another study shows that phosphorus-doped DLC thin films could even be used to produce patterned neuron networks, suggesting that DLC is a candidate coating material for implants in the human nervous system [79]. Commercially, DLC thin films have been used as the coating materials in many applications, for instance, shavers, cutting and drilling tools, protective coating for magnetic media, and optical lenses.…”