Differential Momentary Reports of Stress and Affect Associated With Alcohol Consumption in Middle-Aged Versus Younger Adults

Desire and craving measured using behavioral ratings and brain network topology differ significantly among moderate to heavy alcohol consumers

“…All 39 participants (17 males) were included in the brain imaging analyses. Based on previous findings in this drinking population (Peterson, Laurienti, et al, 2021;Peterson, Mayhugh, et al, 2021),…”

“…All 39 participants (17 males) were included in the brain imaging analyses. Based on previous findings in this drinking population (Peterson, Laurienti, et al, 2021; Peterson, Mayhugh, et al, 2021), along with the results of the statistical analyses of the behavioral ratings, the brain network analyses focused on imaging and behavioral ratings from the alcohol image task in the abstained state. Results demonstrating the interactions of interest in the DMN, depicted in Figures 6 and 7, from both the desire and craving mixed models are included in Table 7, with results from the full models, including all covariates, presented in the Appendix S1.…”

“…Functional brain networks were constructed from BOLD fMRI data; those presented here come from data collected during alcohol image viewing following abstinence, with the theory that the most physiologically relevant results would be found during this period of physiological stress (abstinence) and psychological stress (alcohol image presentation; Peterson, Laurienti, et al, 2021; Peterson, Mayhugh, et al, 2021). Functional networks were generated in the WFU_MMNET Matlab Toolbox (Bahrami et al, 2019; Simpson et al, 2019) by averaging time series data into 268 functionally defined regions classified in the Shen atlas (Shen et al, 2013) and then performing node‐by‐node Pearson correlations.…”

Understanding alcohol use and alcohol use disorders from a developmental psychopathology perspective: Research advances, challenges, and future directions

“…This ostensible healthrelated desistance is reduced by the presence of AUD symptoms, presumably because of higher levels of compulsivity underlying drinking. Stress reduction after drinking may also stronger in midlife than in younger adults, suggested in a small ecological momentary assessment study (Peterson-Sockwell et al, 2024). Finally, unemployment may be more strongly predictive of substance use disorder (including AUD) as individuals age at midlife (although substance use disorder may more weakly predict later unemployment (Kendler et al, 2023).…”