Differential metabolome responses to deltamethrin between resistant and susceptible Anopheles sinensis

Li, Yueyue; Li, Yashu; Wang, Guanxi; Li, Julin; Zhang, Meihua; Wu, J; Liang, Chenyue; HuaYun, Zhou; Tang, Jianxia; Zhu, Guoding

doi:10.1016/j.ecoenv.2022.113553

Cited by 7 publications

(2 citation statements)

References 26 publications

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“…Organooxygen compounds, carboxylic acids, GPs, and purine nucleic acids were shown to be different between resistant and susceptible mosquitos. The GPs route was shared by resistant larva and adults, and it may play an essential role in the metabolic deltamethrin detoxification (Li et al, 2022).…”

Section: Insecticide Resistance Is Integrated With Metabolic Changes ...mentioning

confidence: 99%

The buzz in the field: the interaction between viruses, mosquitoes, and metabolism

Ratnayake

Chotiwan

Saavedra-Rodríguez

et al. 2023

Front. Cell. Infect. Microbiol.

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Among many medically important pathogens, arboviruses like dengue, Zika and chikungunya cause severe health and economic burdens especially in developing countries. These viruses are primarily vectored by mosquitoes. Having surmounted geographical barriers and threat of control strategies, these vectors continue to conquer many areas of the globe exposing more than half of the world’s population to these viruses. Unfortunately, no medical interventions have been capable so far to produce successful vaccines or antivirals against many of these viruses. Thus, vector control remains the fundamental strategy to prevent disease transmission. The long-established understanding regarding the replication of these viruses is that they reshape both human and mosquito host cellular membranes upon infection for their replicative benefit. This leads to or is a result of significant alterations in lipid metabolism. Metabolism involves complex chemical reactions in the body that are essential for general physiological functions and survival of an organism. Finely tuned metabolic homeostases are maintained in healthy organisms. However, a simple stimulus like a viral infection can alter this homeostatic landscape driving considerable phenotypic change. Better comprehension of these mechanisms can serve as innovative control strategies against these vectors and viruses. Here, we review the metabolic basis of fundamental mosquito biology and virus-vector interactions. The cited work provides compelling evidence that targeting metabolism can be a paradigm shift and provide potent tools for vector control as well as tools to answer many unresolved questions and gaps in the field of arbovirology.

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Section: Insecticide Resistance Is Integrated With Metabolic Changes ...mentioning

confidence: 99%

The buzz in the field: the interaction between viruses, mosquitoes, and metabolism

Ratnayake

Chotiwan

Saavedra-Rodríguez

et al. 2023

Front. Cell. Infect. Microbiol.

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“…An altered amino acid metabolism was also reported for deltamethrin resistance in Anopheles sinensis (Li et al, 2022) and Aedes albopictus (Huang et al, 2021), demonstrating that amino acid metabolism is one of the pathways affected by insecticide resistance.…”

Section: Discussionmentioning

confidence: 69%

Multi-omics approaches for understanding spinetoram resistance in >i<Spodoptera frugiperda>/i< (Lepidoptera: Noctuidae)

Kanno

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Multi-omics approaches for understanding spinetoram resistance in Spodoptera frugiperda (Lepidoptera: Noctuidae) / Rubens Hideo Kanno. --versão revisada de acordo com a Resolução CoPGr 6018 de 2011. --Piracicaba, 2023. p.Tese (Doutorado) --USP / Escola Superior de Agricultura "Luiz de Queiroz".1. Lagarta-do-cartucho 2. Espinosinas 3. Genômica 4. Transcritômica 5. Proteômica 6. Metabolômica I. Título I dedicate this work to my parents Toshihiro Kanno and Madalena Akemi Oshita Kanno and my sister Karina SatieKanno, for all the support and incentive during this stage of my life and for always believe on me.To Prof. Dr. Fernando Luis Cônsoli for the guidance, learning, friendship and for always keep the doors of your lab open for me to conduct my experiments.To Dr. Chris Bass (University of Exeter) for the partnership and help with genomics and transcriptomics studies.To Prof. Dr. Carlos Alberto Labate for the partnership and opportunity to conduct the proteomics and metabolomics studies.

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Lemongrass essential oil and its major component citronellol: evaluation of larvicidal activity and acetylcholinesterase inhibition against Anopheles sinensis

Tang,

Li,

Song

2024

Parasitol Res

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Differential metabolome responses to deltamethrin between resistant and susceptible Anopheles sinensis

Cited by 7 publications

References 26 publications

The buzz in the field: the interaction between viruses, mosquitoes, and metabolism

The buzz in the field: the interaction between viruses, mosquitoes, and metabolism

Multi-omics approaches for understanding spinetoram resistance in >i<Spodoptera frugiperda>/i< (Lepidoptera: Noctuidae)

Lemongrass essential oil and its major component citronellol: evaluation of larvicidal activity and acetylcholinesterase inhibition against Anopheles sinensis

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