Differential Inhibition of Xenobiotic-Metabolizing Carboxylesterases by Organotins in Marine Fish

Al-Ghais, Saif M.; Ahmad, Shakeel; Ali, Basharat

doi:10.1006/eesa.2000.1928

Cited by 37 publications

(11 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The former decreasing in mussels collected in areas affected by another oil spill event as well as under lab exposure to crude oil (Moreira et al 2004). We are not aware of any studies measuring CbE in relation to PAHs exposure either, but it has been pointed out as a promising marker in relation to exposure to various organic pollutants in fish studies (Al-Ghais et al 2000;Wheelock et al 2005).…”

Section: Resultsmentioning

confidence: 99%

Stress Biomarkers in Juvenile Senegal Sole, Solea senegalensis, Exposed to the Water-Accommodated Fraction of the “Prestige” Fuel Oil

Solé

Lima

Reis-Henriques

et al. 2007

Bull Environ Contam Toxicol

View full text Add to dashboard Cite

Section: Resultsmentioning

confidence: 99%

Stress Biomarkers in Juvenile Senegal Sole, Solea senegalensis, Exposed to the Water-Accommodated Fraction of the “Prestige” Fuel Oil

Solé

Lima

Reis-Henriques

et al. 2007

Bull Environ Contam Toxicol

View full text Add to dashboard Cite

“…Although this esterase activity is preferentially measured in microsomes because of a high hydrolytic activity (Wheelock et al, 2008;Koenig et al, 2013c), Al-Ghais et al (2000) found that liver CbE activity using pNPA as substrate was higher in the cytosolic fraction of the marine fish Siganus canaliculatus than in microsomes. Mean microsomal CbE activity using pNPA of our fish varied from 40.8 ± 19.2 (M. moro) to 1018 ± 32 nmol/min/mg protein (D. labrax), which were in the same range of variation than those reported for other marine fish species (Al-Ghais et al, 2000;Solé et al, 2010;. We used two model substrates (αNA and pNPA) because of marked differences in substrate preferences by CbEs (Wheelock et al, 2005).…”

Section: Fig 1 Mean: In Nmol/min/mg Protein (±Sem) Carboxylesterasementioning

confidence: 95%

Hepatic biotransformation and antioxidant enzyme activities in Mediterranean fish from different habitat depths

Ribalta

Sánchez-Hernández

Solé

2015

Science of The Total Environment

View full text Add to dashboard Cite

“…Carboxylesterases are also classified as phase I enzymes involved in the hydrolysis of many chemicals and have a relevant role in detoxification and cell protection from chemicals action (Satoh and Hosokawa, 2006;Al-Ghais et al, 2000). Foreign chemicals, but also endogenous compounds (e.g.…”

Section: A C C E P T E D Accepted Manuscriptmentioning

confidence: 99%

Hepatic biomarkers of xenobiotic metabolism in eighteen marine fish from NW Mediterranean shelf and slope waters in relation to some of their biological and ecological variables

Solé

Antó

Baena

et al. 2010

Marine Environmental Research

View full text Add to dashboard Cite

Please cite this article as: Solé, M., Antó, M., Baena, M., Carrasson, M., Cartes, J.E., Maynou, F. Hepatic biomarkers of xenobiotic metabolism in eighteen marine fish from NW Mediterranean shelf and slope waters in relation to some of their biological and ecological variables, Marine Environmental Research (2010), doi: 10.1016/j.marenvres.2010 This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. carboxylesterase and glutathione S-transferase. As markers at higher levels of biological organization, feeding preferences (on benthic, suprabenthic or zooplanktonic species), swimming capability, stomach fullness and trophic level were considered. Significant species differences were found among all the biochemical parameters analysed, although no relationships among the biomarkers themselves were evidenced. In general enzymatic activities were much higher in teleosts than in elasmobranchs, and in perciforms than in gadiforms. Seasonality was observed in some species with higher activities usually corresponding to the winter period. No site related differences were observed in the two selected sites, which differ over a small pollution gradient. A multivariate canonical correspondence analysis (CCA) was performed on shelf and slope species separately to relate biochemical markers with ecological variables. CCA revealed that for shelf species, EROD was positively related to benthos feeding as well as trophic level, while on the slope the clearest association was between suprabenthos feeders and trophic level. Our present results, including seasonality, slightly differ from former observations (Solé et al., 2009a) and reveal a more significant role of the ecological variables in controlling biomarkers expression in fish from the shelf.

show abstract

Differential Inhibition of Xenobiotic-Metabolizing Carboxylesterases by Organotins in Marine Fish

Cited by 37 publications

References 31 publications

Stress Biomarkers in Juvenile Senegal Sole, Solea senegalensis, Exposed to the Water-Accommodated Fraction of the “Prestige” Fuel Oil

Stress Biomarkers in Juvenile Senegal Sole, Solea senegalensis, Exposed to the Water-Accommodated Fraction of the “Prestige” Fuel Oil

Hepatic biotransformation and antioxidant enzyme activities in Mediterranean fish from different habitat depths

Hepatic biomarkers of xenobiotic metabolism in eighteen marine fish from NW Mediterranean shelf and slope waters in relation to some of their biological and ecological variables

Contact Info

Product

Resources

About