Differential gene expression in decidualized human endometrial stromal cells induced by different stimuli
Yumiko Doi-Tanaka,
Isao Tamura,
Amon Shiroshita
et al.
Abstract:Decidualization can be induced by culturing human endometrial stromal cells (ESCs) with several decidualization stimuli, such as cAMP, medroxyprogesterone acetate (MPA) or Estradiol (E2). However, it has been unclear how decidualized cells induced by different stimuli are different. We compared transcriptomes and cellular functions of decidualized ESCs induced by different stimuli (MPA, E2 + MPA, cAMP, and cAMP + MPA). We also investigated which decidualization stimulus induces a closer in vivo decidualization… Show more
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