Abstract:BackgroundChronic pain is frequently experienced by patients with heart failure (HF) and is associated with higher mortality, higher symptom burden, and worsened health-related quality of life. However, the genomic mechanisms underlying chronic pain in HF are understudied. Building an understanding of the mechanistic underpinnings of pain may inform novel interventions.ObjectiveThe objective was to identify genes associated with pain from messenger RNA sequence data collected from patients with HF with and wit… Show more
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