Differential expression of troponin C genes during tongue myogenesis

Prigozy, Theodore I.; Dalrymple, Kirsten; Shuler, Charles F.; Kedes, Larry

doi:10.1002/(sici)1097-0177(199705)209:1<36::aid-aja4>3.0.co;2-y

Cited by 17 publications

(6 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Because muscles of the tongue are not compartmentalized and interdigitate in a variety of planes ( Fig. 1), they have been, historically, very difficult to study as distinct entities New creative techniques have enabled some investigators to overcome these limitations (Prigozy et al, 1997;Sutlive et al, 1999Sutlive et al, , 2000.…”

Section: (I) Introductionmentioning

confidence: 99%

“…Immunohistochemical and molecular genetic techniques have been utilized by Prigozy et al (1997) to type mouse tongue muscle fiber and troponin-C isoforms. They determined that the adult mouse tongue muscle is exclusively composed of fast muscle fibers as defined by the expression of fast Type 11 myosin heavychain proteins (MHC) in the absence of slow Type I isoforms.…”

Section: (I) Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Neural Control of Tongue Movement With Respect To Respiration and Swallowing

Sawczuk

Mosier

2001

Critical Reviews in Oral Biology & Medicine

146

View full text Add to dashboard Cite

The tongue must move with remarkable speed and precision between multiple orofacial motor behaviors that are executed virtually simultaneously. Our present understanding of these highly integrated relationships has been limited by their complexity. Recent research indicates that the tongue s contribution to complex orofacial movements is much greater than previously thought. The purpose of this paper is to review the neural control of tongue movement and relate it to complex orofacial behaviors. Particular attention will be given to the interaction of tongue movement with respiration and swallowing, because the morbidity and mortality associated with these relationships make this a primary focus of many current investigations. This review will begin with a discussion of peripheral tongue muscle and nerve physiology that will include new data on tongue contractile properties. Other relevant peripheral oral cavity and oropharyngeal neurophysiology will also be discussed. Much of the review will focus on brainstem control of tongue movement and modulation by neurons that control swallowing and respiration, because it is in the brainstem that orofacial motor behaviors sort themselves out from their common peripheral structures. There is abundant evidence indicating that the neural control of protrusive tongue movement by motoneurons in the ventral hypoglossal nucleus is modulated by respiratory neurons that control inspiratory drive. Yet, little is known of hypoglossal motoneuron modulation by neurons controlling swallowing or other complex movements. There is evidence, however, suggesting that functional segregation of respiration and swallowing within the brainstem is reflected in somatotopy within the hypoglossal nucleus. Also, subtle changes in the neural control of tongue movement may signal the transition between respiration and swallowing. The final section of this review will focus on the cortical integration of tongue movement with complex orofacial movements. This section will conclude with a discussion of the functional and clinical significance of cortical control with respect to recent advances in our understanding of the peripheral and brainstem physiology of tongue movement.

show abstract

Section: (I) Introductionmentioning

confidence: 99%

Section: (I) Introductionmentioning

confidence: 99%

Neural Control of Tongue Movement With Respect To Respiration and Swallowing

Sawczuk

Mosier

2001

Critical Reviews in Oral Biology & Medicine

146

View full text Add to dashboard Cite

show abstract

“…We thus examined the mRNA expression of markers for skeletal myogenesis in masseter muscles obtained from El 1 to newborn mice. The markers included desmin for myogenic precursor determination (Mayo et al, 1992), muscle creatine kinase for myoblast differentiation (Yaffe, 1969), and troponin C for myofiber maturation (Sutherland et al, 1991;Prigozy et al, 1997). Furthermore, we analyzed the mRNA expression of the myoD family genes which are instrumental in regulating the differentiation and maturation of skeletal muscle (Ludolph and Konieczny, 1995).…”

Section: Introductionmentioning

confidence: 99%

Delayed Embryonic Development of Mouse Masseter Muscle Correlates with Delayed MyoD Family Expression

2000

View full text Add to dashboard Cite

While the masseter muscle is known to have several unique developmental characteristics as compared with other skeletal muscles, little is known about its myogenesis. Thus, we examined the expression of myogenic marker and of myoD family gene mRNA from embryonic day (E) 11 to birth. The obtained results were compared with our earlier results of the mouse tongue muscle, which is also involved in oral functions. The mRNA quantities were determined by means of the reverse-transcription and competitive-polymerase chain-reaction techniques. The expression of myogenic marker mRNA indicated that differentiation and maturation in the masseter began at E13 as in the tongue, and were not yet completed at birth, although they were completed in the tongue. The expression of myoD, myogenin, and myf5 mRNA peaked later in the masseter (E17) than in the tongue (E13). The expression of MRF4 mRNA began later in the masseter (E15) than in the tongue (E13). These results suggest that the delayed expression of the myoD family genes in the masseter correlates with delayed differentiation and maturation, probably due to the later functional requirements of the masseter than of the tongue.

show abstract

“…1986). Myogenesis and synaptogenesis in the tongue are complete earlier than in other muscles such as those of the trunk and limbs (Prigozy et al . 1997;Dalrymple et al .…”

Section: Introductionmentioning

confidence: 99%

Insulin‐like growth factors, hepatocyte growth factor and transforming growth factor‐α in mouse tongue myogenesis

2003

View full text Add to dashboard Cite

Many reports have shown that tongue striated muscles have several unique characteristics not found in other skeletal muscles such as limb and trunk. Several peptide growth factors are reported to play important roles in skeletal myogenesis. In this article, the roles of insulin-like growth factors (IGF), hepatocyte growth factor (HGF) and transforming growth factor (TGF)-alpha in mouse tongue myogenesis were studied using an organ culture system of the mandible or tongue obtained from mouse embryos. It was found that IGF-I promotes the differentiation of tongue myoblasts. HGF plays an essential role in the migration and proliferation of tongue myogenic cells, and inhibits the differentiation of tongue myoblasts. TGF-alpha does not play an essential role in the proliferation of tongue myogenic cells, but does promote the early differentiation of tongue myoblasts. The role of IGF-I in the differentiation of tongue myoblasts, and that of HGF in the migration, proliferation and differentiation of tongue myogenic cells appear to be almost identical to their roles in the myogenesis of limb and cultured myogenic cell lines. However, the role of TGF-alpha in the proliferation and differentiation of tongue myogenic cells appears to be different from its role in the myogenesis of limb and cultured myogenic cell lines such as C2 and L6.

show abstract

Differential expression of troponin C genes during tongue myogenesis

Cited by 17 publications

References 25 publications

Neural Control of Tongue Movement With Respect To Respiration and Swallowing

Neural Control of Tongue Movement With Respect To Respiration and Swallowing

Delayed Embryonic Development of Mouse Masseter Muscle Correlates with Delayed MyoD Family Expression

Insulin‐like growth factors, hepatocyte growth factor and transforming growth factor‐α in mouse tongue myogenesis

Contact Info

Product

Resources

About