Abstract:Changes in endothelial function have been shown to correlate with risk of CVD (1) . Studies investigating endothelial function in premenopausal women must be carefully designed to account for cyclic changes in estrogen, a potent vasoactive hormone (2) . A small number of studies have used flow mediated dilatation (FMD) to investigate the effect of menstrual cycle phase on endothelial function in premenopausal women; both free-cycling (3) , and those taking two different formulations of oral contraceptives (OC)… Show more
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