Differential effects of oxytetracycline on detoxification and antioxidant defense in the hepatopancreas and intestine of Chinese mitten crab under cadmium stress

Zeng, Lin; Wang, Yong-Hong; Ai, Chun-Xiang; Zhang, Bin; Zhang, Hui; Liu, Zi-Ming; Yu, Min-Hui; Hu, Bing

doi:10.1016/j.scitotenv.2024.172633

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

Supporting

Mentioning

Contrasting

Year Published

2024

Publication Types

Select...

Preprint1

Article1

Relationship

Self Cite0

Independent2

Authors

Journals

Cited by 2 publications

References 79 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Concentration-Dependent Effect of Norfloxacin on Fe Transport, Energy Metabolism, and Immunity in the Intestine of Large Yellow Croaker

Zeng,

Wang,

et al. 2024

Preprint

View full text Add to dashboard Cite

Concentration-Dependent Effect of Norfloxacin on Fe Transport, Energy Metabolism, and Immunity in the Intestine of Large Yellow Croaker

Zeng,

Wang,

et al. 2024

Preprint

View full text Add to dashboard Cite

Extraction, Characterization, and Nutraceutical Potential of Prosthechea karwinskii Orchid for Insulin Resistance and Oxidative Stress in Wistar Rats

Barragán-Zarate,

Lagunez-Rivera,

Alexander-Aguilera

et al. 2024

Foods

View full text Add to dashboard Cite

Prosthechea karwinskii is an endemic orchid of Mexico with cultural significance for its ornamental, food, religious, and medicinal uses. In traditional medicine, diabetic patients use the leaves of this plant to lower glucose levels. The present study evaluated the effect of P. karwinskii leaves extract on the antioxidant enzymes superoxide dismutase (SOD) and catalase (CAT) in a model of obese rats with insulin resistance for its nutraceutical potential to reduce insulin resistance and oxidative stress. Obesity and insulin resistance were induced with 40% sucrose in water for 20 weeks. Four groups (control rats, obese rats, obese rats administered the extract, and obese rats administered metformin) were evaluated. Extract compounds were identified by UHPLC-ESI-qTOF-MS/MS. Glucose, insulin, triglyceride, and insulin resistance indices (HOMA-IR and TyG), as well as the activity of the antioxidant enzymes, increased in rats in the obese group. Administration of P. karwinskii extract and metformin reduced glucose, insulin, triglyceride, and insulin resistance indices and antioxidant enzyme activity to values similar to those of the control group. Therefore, this study shows the nutraceutical potential of P. karwinskii extract as an ingredient in the formulation of dietary supplements or functional foods to help treat diseases whose pathophysiology is related to oxidative stress and insulin resistance.

show abstract

Differential effects of oxytetracycline on detoxification and antioxidant defense in the hepatopancreas and intestine of Chinese mitten crab under cadmium stress

Cited by 2 publications

References 79 publications

Concentration-Dependent Effect of Norfloxacin on Fe Transport, Energy Metabolism, and Immunity in the Intestine of Large Yellow Croaker

Concentration-Dependent Effect of Norfloxacin on Fe Transport, Energy Metabolism, and Immunity in the Intestine of Large Yellow Croaker

Extraction, Characterization, and Nutraceutical Potential of Prosthechea karwinskii Orchid for Insulin Resistance and Oxidative Stress in Wistar Rats

Contact Info

Product

Resources

About