Differential effects of noise exposure between substrains of CBA mice

Versteegh, Corstiaen P. C.; Tserga, Evangelia; Fontana, Jacopo Maria; Moreno‐Paublete, Rocio; Sarlus, Heela; Zisiadis, Georgios-Alkis; Cederroth, Christopher R.; Canlon, Barbara

doi:10.1016/j.heares.2021.108395

Cited by 3 publications

(1 citation statement)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In a separate study examining the transcriptomics of neurons within the inferior colliculus, a brain structure vital for sound processing, distinct profiles between day- and nighttime exposure appeared in clock genes [ 490 ]. Furthermore, a phase shift was reported for corticosterone levels in feces of noise-exposed mice, indicating a dysregulated circadian rhythm [ 491 ], which may differ in different mouse strains [ 492 ]. Noise exposure alters clock gene expression ( Per1, Per2, Bmal1, and Rev-Erbα ) in the cochlea and the inferior colliculus, having direct implications for noise-induced hearing loss, but may also be relevant for dysregulated circadian rhythms in other brain regions and remote organs [ 493 ].…”

Section: Pathophysiological Mechanisms Of Noise Exposurementioning

confidence: 99%

Health position paper and redox perspectives - Disease burden by transportation noise

Sørensen,

Pershagen,

Thacher

et al. 2024

Redox Biology

View full text Add to dashboard Cite

Section: Pathophysiological Mechanisms Of Noise Exposurementioning

confidence: 99%

Health position paper and redox perspectives - Disease burden by transportation noise

Sørensen,

Pershagen,

Thacher

et al. 2024

Redox Biology

View full text Add to dashboard Cite

BDNF-enriched small extracellular vesicles protect against noise-induced hearing loss in mice

Min,

Deng,

Lao

et al. 2023

Journal of Controlled Release

View full text Add to dashboard Cite

Sources of variability in auditory brainstem response thresholds in a mouse model of noise-induced hearing loss

Schrode

Dent

Lauer

2022

The Journal of the Acoustical Society of America

View full text Add to dashboard Cite

Numerous and non-acoustic experimental factors can potentially influence experimental outcomes in animal models when measuring the effects of noise exposures. Subject-related factors, including species, strain, age, sex, body weight, and post-exposure measurement timepoints, influence the observed hearing deficits. Experimenter effects, such as experience with experimental techniques and animal handling, may also factor into reported thresholds. In this study, the influence of subject sex, body mass, age at noise exposure, and timepoint of post-exposure recording are reported from a large sample of CBA/CaJ mice. Auditory brainstem response (ABR) thresholds differed between noise-exposed and unexposed mice, although the differences varied across tone frequencies. Thresholds across age at noise exposures and measurement delays after exposure also differed for some timepoints. Higher body mass correlated with higher ABR thresholds for unexposed male and female mice, but not for noise-exposed mice. Together, these factors may contribute to differences in phenotypic outcomes observed across studies or even within a single laboratory.

show abstract

Differential effects of noise exposure between substrains of CBA mice

Cited by 3 publications

References 28 publications

Health position paper and redox perspectives - Disease burden by transportation noise

Health position paper and redox perspectives - Disease burden by transportation noise

BDNF-enriched small extracellular vesicles protect against noise-induced hearing loss in mice

Sources of variability in auditory brainstem response thresholds in a mouse model of noise-induced hearing loss

Contact Info

Product

Resources

About