Alvin J.L. Chia, Christopher E. Goldring, Neil R. Kitteringham, Shi Quan Wong, Paul Morgan, B. Kevin Park
Abstract:Graphical abstractCRMs activate Nrf2, but inhibit NF-κB, and GSH depletion without covalent modification activates both Nrf2 and NF-κB. This leads to cellular protection against the potentially harmful effects of redox perturbation.
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