Differential Diagnosis of Psychiatric Symptoms After Deep Brain Stimulation for Movement Disorders

Psychiatric and Behavioral Complications of GPi DBS in an Adolescent with Myoclonus Dystonia

“…Concerns and questions about the use of pediatric GPi DBS have been raised by many experts, especially when considered for the treatment of several psychiatric illnesses. Even though it is difficult to differentiate the psychiatric symptoms that could be related to the previous neurological condition from neurological damage caused by the GPi DBS or to a comorbid psychiatric condition [11], in the case of this patient, the temporal relationship between the change in frequency of DBS stimulation and presentation of mania and severe aggressive behavior may suggest some association. Larger scale studies are needed to determine causality.…”

Psychiatric Symptoms Associated With Deep Brain Stimulation in an Adolescent With Complex Motor Movement Disorder

“…[1][2][3] Depression was the most common side effect after DBS in one study (N565) and occurred independent of target electrode placement. 5 Emergence of manic symptoms has been associated more with ventral subthalamic DBS placement. 5 Emergence of manic symptoms has been associated more with ventral subthalamic DBS placement.…”

Moria Revisited: Translation of Moritz Jastrowitz’s Description of Pathologic Giddiness

“…Disinhibitions of behavior and emotion are now increasingly recognized to occur in neurologic conditions ranging from chronic traumatic encephalopathy to deep brain stimulation for Parkinson’s disease, but they may evade detection if they are not specifically elicited. 13,14 With this translation of Jastrowitz’s seminal case now available, it is hoped that more attention will be paid to symptoms such as moria in patients with neuropsychiatric diseases.…”