Differential diagnosis of periodic fevers

Regina, Micaela La; Nucera, Gabriella; Diaco, M; Manna, R.; Gasbarrini, Giovanni

doi:10.1136/adc.88.1.92-a

Cited by 3 publications

(2 citation statements)

References 3 publications

(2 reference statements)

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“…Concerns have been raised that other more serious pathologies may be mistaken for PFAPA [4]. For example, pyrexia, stomatitis, and adenopathy may be found in Crohn's disease, in addition to abdominal pain.…”

Section: Diagnosismentioning

confidence: 98%

“…This was later changed to PFAPA in 1989 [3]. It is recognised as part of the differential diagnosis for pyrexia of unknown origin in children, but remains a relatively obscure entity amongst the periodic fever syndromes, which also include familial Mediterranean fever and cyclic neutropenia [4]. Despite the limited available information, it is believed PFAPA has a prolonged course, with a tendency towards self-improvement with time [5,6].…”

Section: Introductionmentioning

confidence: 99%

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Is there a role for the otolaryngologist in PFAPA syndrome?

Leong

Karkos

Apostolidou

2006

International Journal of Pediatric Otorhinolaryngology

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Section: Diagnosismentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Is there a role for the otolaryngologist in PFAPA syndrome?

Leong

Karkos

Apostolidou

2006

International Journal of Pediatric Otorhinolaryngology

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Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: A Tunisian report

Matoussi¹,

Mbarek²,

Fitouri³

et al. 2008

International Journal of Pediatric Otorhinolaryngology Extra

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Whooping cough complicating pulmonary hypertension in pregnancy

Wong

Yan

et al. 2021

BMJ Case Rep

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We report a case of a previously fit woman who presented at 26 weeks into her fourth pregnancy with a dry cough. Following a nasopharyngeal swab, she was diagnosed with a pertussis infection, and treated with antibiotics. A chest X-ray showed right atrial dilatation and an echocardiogram was scheduled outpatient. However, after re-presenting with worsening cough and dyspnoea, an inpatient echocardiogram was performed which suggested elevated pulmonary pressures with significant tricuspid regurgitation, as confirmed by subsequent cardiac catheterisation. She had an elective caesarean section at 34 weeks and underwent repeat right heart catheterisation which revealed persistent, and likely pre-existing, pulmonary arterial hypertension. This case highlights the importance of thorough assessment of non-obstetric symptoms in pregnancy in formulating alternative differentials, even after a diagnosis has been made, to prevent potentially life-threatening conditions from being missed. It also shows that although often associated, respiratory and cardiac causes may coexist separately.

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Differential diagnosis of periodic fevers

Cited by 3 publications

References 3 publications

Is there a role for the otolaryngologist in PFAPA syndrome?

Is there a role for the otolaryngologist in PFAPA syndrome?

Periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome: A Tunisian report

Whooping cough complicating pulmonary hypertension in pregnancy

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