Differential diagnosis of periampullary carcinomas: comparison of CT with negative-contrast CT cholangiopancreatography versus MRI with MR cholangiopancreatography

Wang, Feng-Bo; Ni, Jianming; Zhang, Zhuiyang; Zhang, Lei; Wu, Wenjuan; Wang, Dong; Ji, Yuan; Gong, Lei

doi:10.1007/s00261-014-0085-1

Cited by 7 publications

(2 citation statements)

References 27 publications

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“…But its value is still unsatisfying in the diagnosis in periampullary lesions. Previous studies have reported that the specificity was 75.68-100%, sensitivity was 60-100%, and accuracy was 91.17-92.92% in the diagnosis of periampullary space-occupying lesions [11][12][13][14]. Then, MRCP examination requires a magnetic field, which is contradicted for patients with metal implanted material, such as cardiac pacemaker, metal stent, etc.…”

Section: Introductionmentioning

confidence: 99%

Role of endoscopic ultrasound in the evaluation of unexplained extrahepatic bile duct dilatation

Chen

Wang

Dai

et al. 2022

European Journal of Gastroenterology &Amp; Hepatology

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Objective This study was performed to assess the diagnostic performance of endoscopic ultrasonography (EUS) in patients with extrahepatic bile duct (EBD) dilatation and develop a novel model incorporating EUS-based signature with clinical parameters for distinguishing the malignant dilation of EBD. Methods The EUS data and clinical parameters of the patients were collected and analyzed retrospectively. First, we evaluated the diagnostic performance of EUS in detecting the cause of EBD dilatation. Then, we performed univariate and multivariate binary logistic regression analyses based on clinical and EUS features. Finally, a nomogram was established to aid in distinguishing between malignant dilation and noncalculous benign dilatation of EBD in patients.Results A total of 184 patients were enrolled. For the diagnosis of malignant dilation, EUS achieved an accuracy of 90.76%, sensitivity of 85.96%, and specificity of 92.91%. For the diagnosis of calculous dilation, EUS achieved an accuracy of 100%, sensitivity of 100%, and specificity of 100%. For the diagnosis of noncalculous benign dilatation, EUS achieved an accuracy of 90.76%, sensitivity of 90.90%, and specificity of 90.58%. Multivariable logistic regression analyses indicated that abnormal liver function test, elevated tumor markers, and EUS findings were the well-diagnostic factors of malignant EBD dilation. The nomogram established by these factors showed good calibration and discrimination. Conclusion EUS is a useful examinational modality in the work-up of EBD dilatation. In combination with abnormal liver function test and elevated tumor markers, EUS may provide additional information for the detection of malignant dilation of EBD and should be further investigated.

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Section: Introductionmentioning

confidence: 99%

Role of endoscopic ultrasound in the evaluation of unexplained extrahepatic bile duct dilatation

Chen

Wang

Dai

et al. 2022

European Journal of Gastroenterology &Amp; Hepatology

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“…In addition, MRI requires a magnetic field that is contradicted for patients with cardiac pacemakers, metal clips, or metal stents [8]. Previously, the specificity and accuracy of MRI for PSOLs were found to be 78.3 and 91.5%, respectively [6, 11].…”

Section: Introductionmentioning

confidence: 99%

Combination of CEUS and MRI for the diagnosis of periampullary space-occupying lesions: a retrospective analysis

et al. 2019

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Background The value of magnetic resonance imaging (MRI), contrast-enhanced ultrasound (CEUS), and the combination of CEUS and MRI (CCWM) for the diagnosis of periampullary space-occupying lesions (PSOL) was investigated. Methods A total of 102 patients diagnosed with PSOLs by surgery or biopsy were recruited retrospectively. The sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy of MRI, CEUS, and CCWM were analyzed. Results MRI, CEUS, and CCWM allowed for the accurate detection of 91.17, 92.15, and 99.01% of PSOLs, respectively. The specificity, PPV, and accuracy of CCWM were significantly different from MRI and CEUS ( p < 0.05). However, there the sensitivity and NPV were not significantly different among the three diagnostic technologies. In addition, the specificity, PPV, and accuracy were not significantly different between MRI and CEUS (all p > 0.05). Conclusions CCWM is valuable for differentiating benign and malignant PSOL, which provides important guiding significances for the clinic.

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Periampullary Tumors

Harrison

Lillemoe

2023

The Pancreas

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Differential diagnosis of periampullary carcinomas: comparison of CT with negative-contrast CT cholangiopancreatography versus MRI with MR cholangiopancreatography

Abstract: The CT set provides a comparable performance to that of the MRI set in differentiating periampullary carcinomas, and it may be an alternative to 2D-MRI with MRCP in assessing malignant biliary obstruction in patients who are not suitable for MR examinations.

Cited by 7 publications

References 27 publications

Role of endoscopic ultrasound in the evaluation of unexplained extrahepatic bile duct dilatation

Role of endoscopic ultrasound in the evaluation of unexplained extrahepatic bile duct dilatation

Combination of CEUS and MRI for the diagnosis of periampullary space-occupying lesions: a retrospective analysis

Periampullary Tumors

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