Abstract:Introduction
coronavirus disease 2019 caused by severe acute respiratory syndrome coronavirus 2 was first reported in Wuhan, China. Clinical spectrum of this disease has nonspecific symptoms shared by many other frequent infectious diseases of the respiratory tract and other respiratory tract diseases. This study explains the importance of differential diagnosis between COVID-19 and other lung diseases.
Methods
we analyzed in this study, the demographic features, clinic… Show more
“…При COVID-19 наиболее информативна компьютерная томография грудной клетки: двусторонние изменения в легких по типу «матового стекла» и консолидирующее затенение. При вирусных пневмониях, обусловленных как гриппом, так и MERS-CoV, отмечается снижение сатурации кислорода [8].…”
Influenza remains one of the most common respiratory viral diseases with a high risk of complications. In the context of the COVID-19 pandemic, there is a possibility of simultaneous circulation of two viruses, which makes it necessary to conduct a differential diagnosis. Influenza and COVID-19 have common pathways of transmission of the pathogen and similar symptoms, so the optimal differential diagnosis is the use of test systems for both viruses. Against the background of influenza and COVID-19, complications from various organs and systems can develop. The article describes in detail the complications of influenza from the cardiovascular system. After infection with the flu virus, there is a 6-to 10-fold increase in the risk of acute myocardial infarction and a 3 - to 8-fold increase in the risk of stroke. COVID-19 is associated with arterial hypertension, diabetes mellitus, cardiac arrhythmias, myocarditis, high risk of acute myocardial infarction, and heart failure. The article presents the data of our own research, indicating that the transferred COVID-19 disease increases the risk of acute coronary syndrome, regardless of the presence of risk factors for cardiovascular events. Prevention of the development of influenza complications is the early administration of etiotropic antiviral therapy. Numerous studies confirm the effectiveness of the neuraminidase inhibitor oseltamivir in the treatment of influenza. The use of oseltamivir reduces the severity of clinical manifestations, reduces the duration of the disease, reduces the risk of complications and death. The most effective measure to prevent influenza and COVID-19 is specific immunization. In some cases, chemoprophylaxis can be used. The article discusses studies on the effectiveness of influenza chemoprophylaxis with the use of neuraminidase inhibitors.
“…При COVID-19 наиболее информативна компьютерная томография грудной клетки: двусторонние изменения в легких по типу «матового стекла» и консолидирующее затенение. При вирусных пневмониях, обусловленных как гриппом, так и MERS-CoV, отмечается снижение сатурации кислорода [8].…”
Influenza remains one of the most common respiratory viral diseases with a high risk of complications. In the context of the COVID-19 pandemic, there is a possibility of simultaneous circulation of two viruses, which makes it necessary to conduct a differential diagnosis. Influenza and COVID-19 have common pathways of transmission of the pathogen and similar symptoms, so the optimal differential diagnosis is the use of test systems for both viruses. Against the background of influenza and COVID-19, complications from various organs and systems can develop. The article describes in detail the complications of influenza from the cardiovascular system. After infection with the flu virus, there is a 6-to 10-fold increase in the risk of acute myocardial infarction and a 3 - to 8-fold increase in the risk of stroke. COVID-19 is associated with arterial hypertension, diabetes mellitus, cardiac arrhythmias, myocarditis, high risk of acute myocardial infarction, and heart failure. The article presents the data of our own research, indicating that the transferred COVID-19 disease increases the risk of acute coronary syndrome, regardless of the presence of risk factors for cardiovascular events. Prevention of the development of influenza complications is the early administration of etiotropic antiviral therapy. Numerous studies confirm the effectiveness of the neuraminidase inhibitor oseltamivir in the treatment of influenza. The use of oseltamivir reduces the severity of clinical manifestations, reduces the duration of the disease, reduces the risk of complications and death. The most effective measure to prevent influenza and COVID-19 is specific immunization. In some cases, chemoprophylaxis can be used. The article discusses studies on the effectiveness of influenza chemoprophylaxis with the use of neuraminidase inhibitors.
COVID-19 is characterized by a variety of symptoms that are not pathognomonic, which determines the need for differential diagnosis. COVID-19 refers to acute respiratory infections, has common transmission routes and similar symptoms, simultaneous infection with other respiratory viruses is possible. Symptoms of intoxication require differential diagnosis with other infections, cough and shortness of breath may be manifestations of cardiovascular diseases, ageusia and anosmia occur in respiratory viral infections and neurological diseases, skin manifestations are also not specific. Laboratory and radiation diagnostics in COVID-19 reveals frequent changes, which, however, are also not pathognomonic. The article discusses diseases that have similar manifestations to COVID-19. The greatest difficulties in differential diagnosis are caused by combined conditions the development of COVID-19 in patients with cardiovascular diseases, cancer patients, with chronic diseases of the respiratory system and others. Crucial in the differential diagnosis is the conduct of a specific examination - the determination of the SARS-CoV-2 antigen in smears from the nasopharynx and oropharynx by immunochemical methods.
Objetivo: descrever os desfechos entre a relação da tuberculose e Covid-19 encontrado na literatura. Método: Revisão integrativa sobre a relação da coinfecção tuberculose, a busca se deu no período de novembro de 2019, utilizando as bases de dados Lilacs, Scielo e PubMed. Os descritores utilizados foram tuberculosis, pulmonary, coronavirus infections e diagnosis, aliados ao operador boleano OR. Ao final foram incluídos 6 artigos para análise. Resultado: 50% dos estudos estavam centrados no continente asiático e ou outros 50% na Itália. A coinfecção atinge uma faixa etária diversa, com maior prevalência no sexo masculino. A relação entre elas tem uma taxa significante tanto na gravidade como letalidade. Conclusão: A tuberculose leva a uma progressão mais rápida dos sinais e sintomas da Covid-19, e consequentemente eleva a gravidade, porém quando bem conduzidas à taxa de letalidade é baixa.
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