Differential diagnosis and management of adult-onset laryngomalacia

Ferri, Grace; Prakash, Yash; Levi, Jessica R.; Tracy, Lauren F.

doi:10.1016/j.amjoto.2020.102469

Cited by 8 publications

(13 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…A total of 33 studies were included in our review. [9][10][11] A PRISMA diagram outlining our search is shown in Figure 1. These studies were published from 1987 to 2022 and were conducted in 11 different countries.…”

Section: Included Studies and Patient Demographicsmentioning

confidence: 99%

“…27,46 There were 17 patients from 13 studies with an idiopathic etiology, or one that was not necessarily specified. 11,20,21,[28][29][30][31][32]34,40,43,45,48 Seven studies specifically described the patient's symptoms as adult or acquired laryngomalacia. 11,21,28,30,32,43,48 Four studies reference reports of ALM in their descriptions.…”

Section: Heterogeneity Of Included Patientsmentioning

confidence: 99%

“…10 Most recently, a literature review performed in 2020 revealed 41 reported cases of adult onset laryngomalacia of neurologic, exercise-induced, postoperative, and idiopathic etiologies responding to various management including supraglottoplasty, epiglottidectomy, epiglottopexy, tracheostomy, or simply observation. 11 In a similar category of disease, exercise-induced laryngeal obstruction (EILO) presents with stridor and dyspnea with exertion. 12 This is diagnosed with a continuous laryngoscopy exercise test (CLE-test).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Adult Laryngomalacia: A Scoping Review

Mills,

Monaghan,

Nguyen

et al. 2024

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

ObjectiveThis review sought to determine the characteristics of adults diagnosed with new onset laryngomalacia including airway symptoms, laryngoscopic findings, treatments, and outcomes. Moreover, we wanted to highlight suspected limitations in the literature.Data SourcesStudies were identified through CINAHL, Cochrane Review, PubMed, and Scopus published between 1966 and 2023.Review MethodsThe search was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐analysis Extension for Scoping Reviews checklist by 2 independent investigators. A meta‐analysis of proportions and continuous measures was conducted.ResultsOf the 1121 abstracts identified, 33 articles pertaining to laryngomalacia in the adult population were included. The most common presenting symptoms were stridor at rest (78.3%, 65.1‐88.3) and dyspnea with exertion (83.8%, 64.8‐96.3). The most suspected etiology was exercise‐induced (86.0%, 69.4‐95.5), and the most common description of laryngomalacia on visualization was collapse of supraglottic structures during exercise (93.3%, 79.0‐99.1). Nonsurgical options were attempted in 87.0% (54.0‐99.1), which included oral appliances, respiratory retraining, breathing techniques, and working with a speech pathologist. Surgical options were ultimately performed in 84.2% (75.0‐91.0). Complete resolution of symptoms following therapy was seen in 61.9% (48.0‐74.6).ConclusionAdult onset laryngomalacia is difficult to characterize. It typically presents in patients during exercise, with neurological injury, or idiopathically. Surgical management can lead to improvement or complete resolution of symptoms. The need for a universal nomenclature is highlighted in this review, as it is inconsistently classified.

show abstract

Section: Included Studies and Patient Demographicsmentioning

confidence: 99%

Section: Heterogeneity Of Included Patientsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Adult Laryngomalacia: A Scoping Review

Mills,

Monaghan,

Nguyen

et al. 2024

Otolaryngol.--head neck surg.

View full text Add to dashboard Cite

show abstract

“…Laryngomalacia is the commonest cause of upper airway disorder which affects almost 50% of neonates with stridor [2]. However, adult cases of laryngomalacia (also termed as 'trap-door epiglottis' or 'floppy epiglottis') are considered rare and are often associated with an underlying neurodegenerative disorder [3]. At the time of this report, 41 cases of adult-onset laryngomalacia were reported by Ferri GM et al2 in 2020 and 34% of cases were associated with an underlying neurological disorder.…”

Section: Introductionmentioning

confidence: 99%

“…At the time of this report, 41 cases of adult-onset laryngomalacia were reported by Ferri GM et al2 in 2020 and 34% of cases were associated with an underlying neurological disorder. Surgical options for the treatment of adult-onset laryngomalacia includes supraglottoplasty and tracheostomy [4].Adult-onset laryngomalacia with associated neurological disorders often requires tracheostomy compared to other etiologies such as post-operative,exercise-induced, or idiopathic causes [3,5]which may lead to long term tracheostomy dependency.…”

Section: Introductionmentioning

confidence: 99%

Dual Staged Supraglottoplasty for the Treatment of Trapdoor Epiglottis with Underlying Neurodegenerative Disease–Case report and Review of literature

Syafina

Goh

2021

Indian J Otolaryngol Head Neck Surg

View full text Add to dashboard Cite

To describe the technique and outcome of a novel dual staged supraglottoplasty for the treatment of neurological induced adult onset laryngomalacia. A 55 year old male had a diagnosed neurodegenerative disorder with suspected Pompe's disease associated with Trap door epiglottis and proximal myopathy.This was complicated with emergency airway distress and subsequent tracheostomy.Trap-door epiglottis (also known as adult-onset laryngomalacia) associated with neurodegenerative disorders constitute a surgical challenge as it is often coupled with failure of tracheostomy decannulation when present. The patient underwent a novel dual staged endoscopic supraglottoplasty whereby an initial stage of epiglottopexy and submucosal diathermy was made at the vallecula.This was then followed by an interval of 6 weeks whereby a partial epiglottotectomy was made at the upper 3rd of the epiglottis and reduction of lingual tonsils was done using radiofrequency ablation.Trachesotomy was decannulated 1 month after the second stage procedure and his airway remains asymptomatic after 1 year of surgical treatment. This case report describes the success of tracheostomy decannulation after a novel dual staged supraglottoplasty for adult onset laryngomalcia (also known as trap-door epiglottis) .

show abstract

Abductor Paresis in Shy-Drager Disease

Isozaki

2021

Movement Disorder Emergencies

View full text Add to dashboard Cite

Differential diagnosis and management of adult-onset laryngomalacia

Cited by 8 publications

References 19 publications

Adult Laryngomalacia: A Scoping Review

Adult Laryngomalacia: A Scoping Review

Dual Staged Supraglottoplasty for the Treatment of Trapdoor Epiglottis with Underlying Neurodegenerative Disease–Case report and Review of literature

Abductor Paresis in Shy-Drager Disease

Contact Info

Product

Resources

About