Abstract:Background. Major depressive disorder (MDD) and alcohol use disorders (AUDs) are among the most prevalent psychiatric disorders and are frequently co-morbid. However, some component of this co-morbidity may be artifactual and arise from the influence of current mental state on self-reports of AUD.Method. This study examined whether past-year MDD is associated with differential criterion functioning (DCF) in reports of AUD symptomatology in male and female participants in the National Epidemiological Survey on … Show more
“…The findings of this study do not confirm the current DSM‐IV dichotomy between alcohol abuse and dependence and indicate that DSM‐IV alcohol abuse symptoms are not, as a group, milder that dependence symptoms in this sample. These findings are similar to the findings of several IRT analyses of DSM‐III‐R and DSM‐IV AUD symptoms from a variety of predominantly EuroAmerican samples, including adults (Langenbucher et al., 2004) and adolescents (Martin et al., 2006) from inpatient and outpatient addiction treatment programs, community family studies (Krueger et al., 2004), and the NESARC epidemiologic sample (Kahler et al., 2006; Lynskey and Agrawal, 2008; Saha et al., 2006, 2007). Taken together, the results of this study and these other IRT studies are consistent with the notion that alcohol abuse and dependence diagnoses as currently formulated measure the same disorder in both American Indians and EuroAmericans.…”
Section: Discussionsupporting
confidence: 84%
“…IRT analysis has also been used to examine both past year and lifetime DSM‐IV AUD symptoms in several previous studies of adults and adolescents from epidemiological, community, and treatment samples (Kahler and Strong, 2006; Kirisci et al., 2006; Krueger et al., 2004; Langenbucher et al., 2004; Lynskey and Agrawal, 2008; Martin et al., 2006; Saha et al., 2006). In general, these studies of have found that alcohol abuse and dependence symptoms are intermixed in terms of severity and that AUD symptoms occupied the moderate and severe portions of the severity continuum.…”
Background
Item Response Theory (IRT) has been used to examine alcohol use disorder (AUD) symptoms and their psychometric properties but has not been previously applied to AUD symptoms from an American Indian sample.
Methods
Lifetime DSM-IV AUD symptoms and binge drinking (5+ drinks men/4+ drinks women) at ≥1, ≥4, ≥8, ≥15 days per month during the period of heaviest lifetime drinking criteria were assessed in 530 American Indian participants. Exploratory (EFA) factor analysis was used to examine the factor structure of the ten AUD symptoms and each alcohol consumption criterion. Two-parameter IRT models generated marginal maximum likelihood estimates for discrimination (a) and threshold (b) parameters for ten DSM-IV AUD symptoms and each consumption criterion. Differential Item Functioning (DIF) analysis was used to assess AUD symptom severity in groups defined by gender and age at interview.
Results
The AUD symptoms of “Withdrawal” and “Activities Given Up” were the most severe symptoms. “Tolerance” and “Social/Interpersonal Problems” were the least severe. All AUD symptoms fell on the moderate portion of the severity continuum, except “Withdrawal”, which fell at the lower end of the severe portion. The consumption criterion of 5+/4+ (male/female) at ≥8 times per month demarcated the portion of the severity continuum where AUD symptoms began to occur at a probability of 50%. DIF analysis showed significant gender and age at interview differences for “Hazardous Use,” “Tolerance,” and “Activities Given Up,” but not for the other AUD symptoms.
Conclusions
In this American Indian community sample, alcohol abuse and dependence did not represent distinct disorders. Only one AUD symptom was found outside the moderate portion of the underlying AUD severity continuum. Drinking 5+/4+ (male/female) drinks at a frequency of ≥8 times per month during the period of heaviest lifetime drinking was found to function well as both a risk and a diagnostic criterion for lifetime DSM-IV AUD. DSM-IV AUD symptom criteria, as currently assessed, may be limited in their ability to capture the full range of symptom severity of AUDs, at least in this high risk population.
“…The findings of this study do not confirm the current DSM‐IV dichotomy between alcohol abuse and dependence and indicate that DSM‐IV alcohol abuse symptoms are not, as a group, milder that dependence symptoms in this sample. These findings are similar to the findings of several IRT analyses of DSM‐III‐R and DSM‐IV AUD symptoms from a variety of predominantly EuroAmerican samples, including adults (Langenbucher et al., 2004) and adolescents (Martin et al., 2006) from inpatient and outpatient addiction treatment programs, community family studies (Krueger et al., 2004), and the NESARC epidemiologic sample (Kahler et al., 2006; Lynskey and Agrawal, 2008; Saha et al., 2006, 2007). Taken together, the results of this study and these other IRT studies are consistent with the notion that alcohol abuse and dependence diagnoses as currently formulated measure the same disorder in both American Indians and EuroAmericans.…”
Section: Discussionsupporting
confidence: 84%
“…IRT analysis has also been used to examine both past year and lifetime DSM‐IV AUD symptoms in several previous studies of adults and adolescents from epidemiological, community, and treatment samples (Kahler and Strong, 2006; Kirisci et al., 2006; Krueger et al., 2004; Langenbucher et al., 2004; Lynskey and Agrawal, 2008; Martin et al., 2006; Saha et al., 2006). In general, these studies of have found that alcohol abuse and dependence symptoms are intermixed in terms of severity and that AUD symptoms occupied the moderate and severe portions of the severity continuum.…”
Background
Item Response Theory (IRT) has been used to examine alcohol use disorder (AUD) symptoms and their psychometric properties but has not been previously applied to AUD symptoms from an American Indian sample.
Methods
Lifetime DSM-IV AUD symptoms and binge drinking (5+ drinks men/4+ drinks women) at ≥1, ≥4, ≥8, ≥15 days per month during the period of heaviest lifetime drinking criteria were assessed in 530 American Indian participants. Exploratory (EFA) factor analysis was used to examine the factor structure of the ten AUD symptoms and each alcohol consumption criterion. Two-parameter IRT models generated marginal maximum likelihood estimates for discrimination (a) and threshold (b) parameters for ten DSM-IV AUD symptoms and each consumption criterion. Differential Item Functioning (DIF) analysis was used to assess AUD symptom severity in groups defined by gender and age at interview.
Results
The AUD symptoms of “Withdrawal” and “Activities Given Up” were the most severe symptoms. “Tolerance” and “Social/Interpersonal Problems” were the least severe. All AUD symptoms fell on the moderate portion of the severity continuum, except “Withdrawal”, which fell at the lower end of the severe portion. The consumption criterion of 5+/4+ (male/female) at ≥8 times per month demarcated the portion of the severity continuum where AUD symptoms began to occur at a probability of 50%. DIF analysis showed significant gender and age at interview differences for “Hazardous Use,” “Tolerance,” and “Activities Given Up,” but not for the other AUD symptoms.
Conclusions
In this American Indian community sample, alcohol abuse and dependence did not represent distinct disorders. Only one AUD symptom was found outside the moderate portion of the underlying AUD severity continuum. Drinking 5+/4+ (male/female) drinks at a frequency of ≥8 times per month during the period of heaviest lifetime drinking was found to function well as both a risk and a diagnostic criterion for lifetime DSM-IV AUD. DSM-IV AUD symptom criteria, as currently assessed, may be limited in their ability to capture the full range of symptom severity of AUDs, at least in this high risk population.
“…That said, it is reasonable to assume that given the extensive process of informed consent and assurances of confidentiality that data were reliable and valid, providing ample information for the current analysis. DCF analyses were exploratory in nature and did not specifically control for alternative factors (either measured or unmeasured) other than the attributes we chose that may have influenced criteria endorsement, such as depression in the case of gender (Lynskey & Agrawal, 2008). Finally, inclusion of individuals 50 to 65 limits our ability to generalize our results to an older adult population 65 and older.…”
This study explored dimensionality and rank-order severity of the Diagnostic and Statistical Manual of Mental Disorders fourth edition (DSM-IV) alcohol use disorder (AUD) criteria among adults 50+ years old. Secondary analysis was performed on data from individuals 50+ (N = 3,412) from the 2009 National Survey of Drug Use and Health. Confirmatory factor analyses (CFA) and item response theory (IRT) analyses were performed on the 11 AUD criteria. DSM-IV and DSM fifth edition (DSM-5) classifications were compared. CFA revealed a one-factor model. IRT analyses revealed that AUD criteria identify only severe cases of AUD. Overall, 5.8% met criteria for a DSM-IV AUD; 7.5% met criteria for DSM-5 AUD.
“…About one in five women will develop an episode of major depression in their lives (Hasin et al, 2005) and these women are at increased risk to also be engaging in alcohol misuse (Lynskey & Agrawal, 2008). In this study, women who had experienced an episode of major depression in the last year were significantly more likely to have problems related to alcohol use, such as drunk driving, conflicts with others, or job difficulties.…”
Section: Discussionmentioning
confidence: 99%
“…Alcohol misuse is frequently comorbid with depression in women. For example, data from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) showed that women with major depressive disorder were more likely than non-depressed women to report multiple criteria for alcohol abuse and dependence (Lynskey & Agrawal, 2008). Research has also repeatedly found associations of women’s depression with binge drinking.…”
Background
Depression and alcohol-related problems are often comorbid in women, but not all depressed women have comorbid alcohol-related problems. The current study investigated intrapersonal (drinking expectancies), interpersonal (interpersonal pressure to drink), and familial (mother’s and father’s drinking history) predictors of alcohol-related problems among women with and without a major depressive episode in the past year.
Method
Participants were 853 women ages 21–90 from a U.S. national probability sample. Depression diagnosis was determined via interviewer administration of the Diagnostic Interview Schedule (DIS) depression module. Participants completed self-report measures of alcohol-related problems and intrapersonal, interpersonal, and familial predictors of drinking.
Results
Regression analyses indicated that an episode of depression in the past year, more positive drinking expectancies, greater interpersonal pressure to drink, and higher levels of maternal (but not paternal) drinking predicted alcohol-related problems; moreover, the relationships between alcohol-related problems and maternal drinking, paternal drinking, and interpersonal pressure to drink were significantly stronger among women with an episode of major depression in the past year than among women without an episode.
Limitations
Study data was cross-sectional and obtained through self-report, thus limiting causal explanations of results.
Conclusions
Findings suggest that depression may enhance the impact of interpersonal and familial risk factors on women’s alcohol misuse. Implications of findings for transdiagnostic models of psychopathology and for prevention and treatment of alcohol-related problems in women presenting with depressive symptoms are discussed.
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