Differential brain responses for perception of pain during empathic response in binge drinkers compared to non-binge drinkers

Rae, Charlotte L.; Gierski, Fabien; Smith, Kathleen W.; Nikolaou, Kyriaki; Davies, Amy; Critchley, Hugo; Naassila, Mickaël; Duka, Theodora

doi:10.1016/j.nicl.2020.102322

Cited by 12 publications

(12 citation statements)

References 53 publications

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“…Cross-sectional studies indicate that drinkers produced lower activation in the middle frontal gyrus while decoding vocal affective bursts (P. Maurage et al, 2013) and in the fusiform gyrus when perceiving others' pain (Rae et al, 2020), with implications for impairments in emotion recognition and empathy. Longitudinal studies support the observation of reduced activations in frontal and striatal networks during inhibition among adolescents with a history of binge drinking over 3 years (Norman et al, 2011;Wetherill et al, 2013).…”

Section: Brain Structural and Functional Declines Related To Hazardou...mentioning

confidence: 99%

Alcohol drinking and alcohol use disorder across the ages: Dynamic effects on the brain and function.

Sullivan¹,

Lannoy²,

Berre³

et al. 2023

APA Handbook of Neuropsychology, Volume 1: Neurobehavioral Disorders and Conditions: Accepted Science and Open Questions (Vol.

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This chapter focuses on (a) the epidemiology and diagnosis of alcohol use disorder (AUD); (b) neuroradiological signatures of syndromes of AUD and concomitant signs and symptoms; (c) the dynamic course of component neuropsychological processes in drinking and sobriety; and (d) the effects of adolescent drinking on cognitive, motor, and brain function. The conclusion provides a summary of accepted facts about AUD and identifies salient questions about AUD remaining to be answered. WHAT THE FIELD KNOWS Epidemiology and Definition of Excessive Drinking and Alcohol Use DisorderEpidemiology. The World Health Organization (WHO; 2018) Global Status Report on Alcohol and Health 2018 estimated rates of AUD in the United States at 3% to 6% of the population, with a nearly 30% lifetime AUD prevalence. Despite its high prevalence, fewer than 10% of individuals with AUD receive treatment. Determination of drinking patterns considers consumption amount and frequency in the context of National Institute on Alcohol Abuse and Alcoholism (NIAAA) guidelines, which recommend no more than one drink per day (maximum seven drinks per week) for women, no more than two drinks on any one day (maximum 14 drinks per week) for men, and never to drink while pregnant or when planning a pregnancy. Alcohol consumption is increasing among people approaching retirement age, with women exceeding the trajectory increase of men both in regular to heavy drinking and binge drinking (Breslow et al., 2017), although an increase in frequent heavy drinking has also been documented in older men (Han et al., 2019). Binge drinking is defined as consuming more than four (for women) or five (for men) alcohol drinks in 2 hours (NIAAA, 2020).An AUD diagnosis is made based on the criteria listed in the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5; American Psychiatric Association, 2013) or the International Statistical Classification of Disease and Related Health Problems, 10th revision (ICD-10; WHO, 2016). These diagnostic codes depict AUD on a severity spectrum from mild to severe. "Alcohol abuse and alcohol dependence" as a diagnosis is no longer in the nosology. The DSM-5 diagnosis has 11 criteria; the presence of two or more within a 12-month span qualifies as an AUD. Especially relevant to recognizing how AUD contributes to cognitive compromise of frontally based functions involving social cognition and perseveration are two criteria:

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Section: Brain Structural and Functional Declines Related To Hazardou...mentioning

confidence: 99%

Alcohol drinking and alcohol use disorder across the ages: Dynamic effects on the brain and function.

Sullivan¹,

Lannoy²,

Berre³

et al. 2023

APA Handbook of Neuropsychology, Volume 1: Neurobehavioral Disorders and Conditions: Accepted Science and Open Questions (Vol.

View full text Add to dashboard Cite

show abstract

“…This score was calculated for all participants on the basis of the information provided regarding core characteristics of BD: consumption speed (average drinks per hour), drunkenness episodes (number of times being drunk in the previous 6 months) and the drunkenness ratio (percentage of times getting drunk when drinking). The AUQ-R binge score is a validated and widely used method for exploring binge drinking (e.g., Czapla et al, 2015;Rae et al, 2020;Townshend & Duka, 2005;Townshend et al, 2014).…”

Section: Alcohol Usementioning

confidence: 99%

Role of Impulsivity and Emotion Dysregulation Dimensions on Core Characteristics of Binge Drinking among University Students

Benzerouk

Djerada

Naassila

et al. 2022

Psychologica Belgica

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Binge drinking refers to a pattern of alcohol consumption that leads to rapid intoxication followed by withdrawal and abstinence periods. This study aimed to investigate the potential differential contributions of impulsivity and emotion regulation difficulties to core characteristics of binge drinking (consumption speed, frequency of binge drinking episodes, and the ratio of binge drinking episodes) among a sample of non-abstainers college students. One thousand and five hundred fifty-five participants (17-25 years old) completed the UPPS-P Impulsive behavior scale, the Difficulties in Emotion Regulation Scale (DERS) and measures related to alcohol consumption patterns and affects by means of an online survey. Multiple regression analyses showed that UPPS-P sensation seeking, lack of premeditation, positive, and negative urgency dimensions were significantly associated with binge drinking core characteristics. More specifically, lack of premeditation, and sensation seeking dimensions were associated with speed of drinking, frequency of binge drinking epiosodes, and the ratio of binge drinking episodes. Positive urgency was associated with speed of drinking, and the ratio of binge drinking episodes while negative urgency was negatively associated with speed of drinking. DERS impulse dimension was associated with speed of drinking, DERS awareness dimension was negatively associated with the frequency of binge drinking episodes, and DERS goals dimension was significantly associated with the ratio of binge drinking episodes. Furthermore, patterns of drinking were independently associated with sex, depression and anxiety scores. These findings may help to plan and develop interventions aimed at addressing binge drinking in young adults by targeting impulsivity and emotion dysregulation.

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“…(2017b) , with participants divided into three groups (non-responders, S/L and A/G), and in which they were asked to rate their own vicarious pain response to seeing painful and non-painful images. Dataset 2 uses a sample of students from Rae et al . (2020) who we would assume would be primarily non-responders.…”

Section: Introductionmentioning

confidence: 99%

Can the neural representation of physical pain predict empathy for pain in others?

Li,

Racey,

Rae

et al. 2024

Social Cognitive and Affective Neuroscience

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The question of whether physical pain and vicarious pain have some shared neural substrates is unresolved. Recent research has argued that physical and vicarious pain are represented by dissociable multivariate brain patterns by creating biomarkers for physical pain (Neurologic Pain Signature, NPS) and vicarious pain (Vicarious Pain Signature, VPS) respectively. In the current research, the NPS and two versions of the VPS were applied to three fMRI datasets (one new, two published) relating to vicarious pain which focused on between-subject differences in vicarious pain (Datasets 1 and 3) and within-subject manipulations of perspective taking (Dataset 2). Results show that (1) NPS can distinguish brain responses to images of pain versus no-pain and to a greater extent in vicarious pain responders who report experiencing pain when observing pain, (2) neither version of the VPS mapped on to individual differences in vicarious pain and the two versions differed in their success in predicting vicarious pain overall. This study suggests that the NPS (created to detect physical pain) is, under some circumstances, sensitive to vicarious pain and there is significant variability in VPS measures (created to detect vicarious pain) to act as generalizable biomarkers of vicarious pain.

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Differential brain responses for perception of pain during empathic response in binge drinkers compared to non-binge drinkers

Cited by 12 publications

References 53 publications

Alcohol drinking and alcohol use disorder across the ages: Dynamic effects on the brain and function.

Alcohol drinking and alcohol use disorder across the ages: Dynamic effects on the brain and function.

Role of Impulsivity and Emotion Dysregulation Dimensions on Core Characteristics of Binge Drinking among University Students

Can the neural representation of physical pain predict empathy for pain in others?

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