“…Lipschutz and Quintana (248,251) studied the inactivation of estrogens in the form of intrasplenic or intrahepatic pellets. These workers confirmed the observation that inactivation of synthetics takes place but to a lesser degree than with natural estrogens.…”
Section: Metabolic Conversion and Efficacy By Various Routesmentioning
“…Lipschutz and Quintana (248,251) studied the inactivation of estrogens in the form of intrasplenic or intrahepatic pellets. These workers confirmed the observation that inactivation of synthetics takes place but to a lesser degree than with natural estrogens.…”
Section: Metabolic Conversion and Efficacy By Various Routesmentioning
“…In the rabbit and guinea pig splenic implants of crystalline steroids are inactive, demonstrating hepatic inactivation (Biskind and Meyer (82), Lipschutz et at. (83)). Employing the technique of splenic implantation of estrone and estradiol, Biskind and Biskind (84) found that ovariectomized rats would show signs of constant estrus in about ten days when fed a diet deficient in the components of the vitamin B complex.…”
Section: Interrelation Between Vitamins and Estrogensmentioning
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.